NME4 and CFAP206

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NME4	CFAP206
Description		NME/NM23 nucleoside diphosphate kinase 4	cilia and flagella associated protein 206
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Membrane	Radial Spoke Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Ciliary Basal Body Cell Projection A Axonemal Microtubule
	Molecular Function	Nucleotide Binding Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Phospholipid Binding Lipid Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding GTPase Binding Phosphatidylglycerol Transfer Activity Mitochondrion-mitochondrion Outer Membrane Tether Activity Cardiolipin Binding	Protein Binding
	Biological Process	GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Lipid Transport Nucleoside Metabolic Process Nucleotide Metabolic Process Protein Hexamerization Intermembrane Phospholipid Transfer	Cilium Movement Regulation Of Cilium Beat Frequency Sperm Axoneme Assembly Cell Projection Organization Axoneme Assembly Regulation Of Flagellated Sperm Motility
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Body mass index ( 26426971) Red blood cell traits ( 23446634)
Interacting Genes		39 interacting genes: ABI2 AIRIM ARMC7 ATPAF2 C14orf119 CABP2 CABP5 CCDC102B CCDC57 CDKN2D CFAP206 CIB1 CIB3 CIDEB CLNK DTX2 HDAC7 HSF2BP LMO4 LSM8 MKRN3 MLH1 NME1 NME7 NUTF2 NXF1 POLR1C PSMB1 SOCS3 SPG21 SUV39H2 TNS4 TRAPPC2 TRAPPC2B TRIP13 TSSK3 TTC19 UBL5 ZBTB16	64 interacting genes: ADAMTSL4 ANKRD55 APIP ATPAF2 BANP BLZF1 C1orf94 C9orf153 CCDC33 CDX2 CEP57L1 CFP CPSF7 CRX CYSRT1 DISC1 EIF4ENIF1 GFAP GLYR1 GPRASP2 GSE1 HOMEZ IHO1 IKZF3 KIAA1328 KLHL3 KRT31 KRT34 KRT40 KRT75 KRT76 KRTAP13-1 KRTAP26-1 LZTS2 MAGED1 MDFI MEOX2 MIF4GD NME4 PIH1D2 PRDM16 PSMA1 PSMC5 REL RNF138 ROCK1 SAMD3 SAXO1 SORBS3 SOX30 TADA2B TASOR2 TCF12 TEKT1 TFIP11 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 VPS52 ZBTB32 ZNF511
Entrez ID		4833	154313
HPRD ID		03489	12863
Ensembl ID		ENSG00000103202	ENSG00000272514
Uniprot IDs		A0A087WVT9 O00746	Q8IYR0 Q8N771
PDB IDs		1EHW
Enriched GO Terms of Interacting Partners?		Protein Binding Male Meiotic Nuclear Division Male Germ Cell Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process 3'-5'-DNA Exonuclease Activity Female Meiosis I CTP Metabolic Process CTP Biosynthetic Process TRAPPII Protein Complex TRAPPIII Protein Complex Meiosis I Cell Cycle Process Nucleoside Diphosphate Kinase Activity TRAPP Complex Meiotic Nuclear Division Filopodium Tip Female Meiotic Nuclear Division	Keratin Filament Intermediate Filament Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Protein Binding Structural Molecule Activity
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