NME4

Description		NME/NM23 nucleoside diphosphate kinase 4
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Membrane
	Molecular Function	Nucleotide Binding Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Phospholipid Binding Lipid Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding GTPase Binding Phosphatidylglycerol Transfer Activity Mitochondrion-mitochondrion Outer Membrane Tether Activity Cardiolipin Binding
	Biological Process	GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Lipid Transport Nucleoside Metabolic Process Nucleotide Metabolic Process Protein Hexamerization Intermembrane Phospholipid Transfer
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Body mass index ( 26426971) Red blood cell traits ( 23446634)
Interacting Genes		39 interacting genes: ABI2 AIRIM ARMC7 ATPAF2 C14orf119 CABP2 CABP5 CCDC102B CCDC57 CDKN2D CFAP206 CIB1 CIB3 CIDEB CLNK DTX2 HDAC7 HSF2BP LMO4 LSM8 MKRN3 MLH1 NME1 NME7 NUTF2 NXF1 POLR1C PSMB1 SOCS3 SPG21 SUV39H2 TNS4 TRAPPC2 TRAPPC2B TRIP13 TSSK3 TTC19 UBL5 ZBTB16
Entrez ID		4833
HPRD ID		03489
Ensembl ID		ENSG00000103202
Uniprot IDs		A0A087WVT9 O00746
PDB IDs		1EHW
Enriched GO Terms of Interacting Partners?		Protein Binding Male Meiotic Nuclear Division Male Germ Cell Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process 3'-5'-DNA Exonuclease Activity Female Meiosis I CTP Metabolic Process CTP Biosynthetic Process TRAPPII Protein Complex TRAPPIII Protein Complex Meiosis I Cell Cycle Process Nucleoside Diphosphate Kinase Activity TRAPP Complex Meiotic Nuclear Division Filopodium Tip Female Meiotic Nuclear Division
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