BCKDK and NR5A2

Number of citations of the paper that reports this interaction (PMID 15604093)
36

Data Source:
BioGRID (two hybrid)

		BCKDK	NR5A2
Gene Name		branched chain ketoacid dehydrogenase kinase	nuclear receptor subfamily 5, group A, member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Phospholipid Binding Zinc Ion Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Protein Phosphorylation Cellular Amino Acid Catabolic Process Branched-chain Amino Acid Catabolic Process Phosphorylation	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Bile Acid Metabolic Process Embryo Development Gene Expression Intracellular Receptor Signaling Pathway Endocrine Pancreas Development Regulation Of Cell Proliferation Homeostatic Process Cholesterol Homeostasis Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Viral Genome Replication Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS			Pancreatic cancer ( 20101243)
Protein-Protein Interactions		6 interactors: APP EPS8 LSM8 NR5A2 STAT3 TRAF4	19 interactors: ALB BCKDK COPS5 EDF1 FTH1 NCOA1 NCOA3 NPPA NR0B2 NRIP1 NSD1 PNRC1 PNRC2 POLR2D PROX1 RAD54L2 SMARCD3 SRC UBE2I
Entrez ID		10295	2494
HPRD ID		12523	06830
Ensembl ID		ENSG00000103507	ENSG00000116833
Uniprot IDs		A8MY43 O14874 Q96G95	B4E2P3 F1D8R9 O00482
PDB IDs			1YOK 1YUC 1ZDU 2A66 3PLZ 3TX7 4DOR 4DOS 4IS8
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Feeding Behavior Regulation Of Multicellular Organism Growth Behavior Adult Locomotory Behavior Synaptic Growth At Neuromuscular Junction Response To Ethanol Regulation Of Protein Binding Adult Behavior Collateral Sprouting In Absence Of Injury Actin Polymerization-dependent Cell Motility Chemical Homeostasis Collateral Sprouting Axon Midline Choice Point Recognition Locomotory Behavior Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Axon Choice Point Recognition Exit From Mitosis Steroid Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Binding Negative Regulation Of Glycolytic Process Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Regulation Of Signal Transduction Neuron Remodeling Radial Glial Cell Differentiation Behavioral Response To Ethanol Positive Regulation Of Protein Homodimerization Activity Signal Transduction Positive Regulation Of Signal Transduction Negative Regulation Of Cell Development Positive Regulation Of Transcription, DNA-templated Organ Development Homeostatic Process Regulation Of Signaling Interleukin-6-mediated Signaling Pathway Signaling Cell Communication RNA Metabolic Process Rac Protein Signal Transduction Movement Of Cell Or Subcellular Component Positive Regulation Of Macromolecule Biosynthetic Process MRNA Processing Cellular Copper Ion Homeostasis Positive Regulation Of Gene Expression Regulation Of Protein Homodimerization Activity Positive Regulation Of Metabolic Process Single-organism Behavior	Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Intracellular Steroid Hormone Receptor Signaling Pathway Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Androgen Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Metabolic Process Cellular Metabolic Process Metabolic Process Regulation Of Cellular Process Transcription From RNA Polymerase II Promoter Peptidyl-lysine Modification Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated Labyrinthine Layer Morphogenesis Positive Regulation Of Organelle Assembly Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryonic Placenta Morphogenesis Gland Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Response To Nutrient Levels Mammary Gland Development Anatomical Structure Development Negative Regulation Of Gene Expression Response To Extracellular Stimulus Negative Regulation Of Biosynthetic Process
Tagcloud ?		administering afforded akt3 ameliorated asd autism autisms clues cntn5 cntnap2 cyfip1 en2 fmr1 individually mecp2 neuroanatomical neuroligins neurorexins personalized pharmacologic phenotypically plausible polygenic scn1a shank2 siblings slc6a4 tailored tsc1	4f 6f boosts copyright dn endogenously epiblast episcs feeder impedes ipscs klf4 lrh1 mef mefs n2b27 oct4 pluripotency pluripotent primed rarg reprogram reprogramming reprograms reserved rights sox2 supplementing synthesised
Tagcloud (Difference) ?		administering afforded akt3 ameliorated asd autism autisms clues cntn5 cntnap2 cyfip1 en2 fmr1 individually mecp2 neuroanatomical neuroligins neurorexins personalized pharmacologic phenotypically plausible polygenic scn1a shank2 siblings slc6a4 tailored tsc1	4f 6f boosts copyright dn endogenously epiblast episcs feeder impedes ipscs klf4 lrh1 mef mefs n2b27 oct4 pluripotency pluripotent primed rarg reprogram reprogramming reprograms reserved rights sox2 supplementing synthesised
Tagcloud (Intersection) ?