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SUFU and ZNF219
Number of citations of the paper that reports this interaction (PMID
14611647
)
23
Data Source:
HPRD
(two hybrid)
SUFU
ZNF219
Gene Name
suppressor of fused homolog (Drosophila)
zinc finger protein 219
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Primary Cilium
Ciliary Tip
Ciliary Base
Nucleus
Integral Component Of Membrane
Molecular Function
Transcription Corepressor Activity
Signal Transducer Activity
Protein Binding
Beta-catenin Binding
Transcription Factor Binding
Protein Kinase Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Histamine Receptor Activity
Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Skeletal System Development
Neural Tube Closure
Heart Looping
Regulation Of Transcription, DNA-templated
Proteolysis
Signal Transduction
Multicellular Organismal Development
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification
Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification
Negative Regulation Of Transcription Factor Import Into Nucleus
Cytoplasmic Sequestering Of Transcription Factor
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Skin Development
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Smoothened Signaling Pathway
Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Neurotransmitter Levels
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Pathways
Hedgehog 'off' state
Hedgehog 'on' state
Signaling by Hedgehog
Degradation of GLI1 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Degradation of GLI2 by the proteasome
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
26 interactors:
BTRC
GLI1
GLI2
GLI3
GLIS3
HDX
HMGA1
HNRNPA1
LAMTOR3
LGALS3
MID1IP1
NCOA3
PEX26
PIAS1
QPRT
RBPJ
RCN3
RNF19A
SAP18
SETDB1
STK36
ZNF219
ZNF263
ZNF446
ZNF747
ZNF764
11 interactors:
BCL2L1
CDK4
CSNK2A2
CTBP1
LMO1
MAPK3
MAPK8
SH3GL2
SH3KBP1
SUFU
TTC32
Entrez ID
51684
51222
HPRD ID
06124
05435
Ensembl ID
ENSG00000107882
ENSG00000165804
Uniprot IDs
Q9UMX1
Q9P2Y4
PDB IDs
1M1L
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Smoothened Signaling Pathway
Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Notochord Regression
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Mammary Gland Morphogenesis
Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification
Tube Morphogenesis
Smoothened Signaling Pathway
Smoothened Signaling Pathway Involved In Regulation Of Cerebellar Granule Cell Precursor Cell Proliferation
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Ventral Midline Development
Gland Development
Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Organ Formation
Proximal/distal Pattern Formation
Cerebellar Purkinje Cell-granule Cell Precursor Cell Signaling Involved In Regulation Of Granule Cell Precursor Cell Proliferation
Pituitary Gland Development
Gland Morphogenesis
Positive Regulation Of Neural Precursor Cell Proliferation
Mammary Gland Development
Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation
Regulation Of Chromosome Organization
Regulation Of Cellular Component Organization
Regulation Of Histone Modification
Regulation Of Organelle Organization
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Cell Surface Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Neurotrophin Signaling Pathway
Protein Phosphorylation
Regulation Of Histone Deacetylation
Endocytosis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Signal Transduction
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Histone Acetylation
Regulation Of Protein Deacetylation
Negative Regulation Of Protein Binding
Regulation Of Metabolic Process
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Signaling
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Cell Part Morphogenesis
TRIF-dependent Toll-like Receptor Signaling Pathway
Cell Communication
Regulation Of Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Cell Cycle
MyD88-dependent Toll-like Receptor Signaling Pathway
Cellular Response To Mechanical Stimulus
Positive Regulation Of Histone Modification
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Apoptotic Process In Bone Marrow
Negative Regulation Of Apolipoprotein Binding
Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification
Negative Regulation Of Cellular Protein Catabolic Process
Tagcloud
?
beta1
blots
cck
colorectal
constructed
counting
enhances
gli1
hedgehog
hh
ht29
infecting
integrin
interference
invasion
itgb1
kit
lentiviral
lentivirus
malignancies
migrating
rnai
shh
sonic
transwell
unrelated
vectors
xenografted
xenografting
Tagcloud (Difference)
?
beta1
blots
cck
colorectal
constructed
counting
enhances
gli1
hedgehog
hh
ht29
infecting
integrin
interference
invasion
itgb1
kit
lentiviral
lentivirus
malignancies
migrating
rnai
shh
sonic
transwell
unrelated
vectors
xenografted
xenografting
Tagcloud (Intersection)
?