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SUFU and RNF19A
Number of citations of the paper that reports this interaction (PMID
14611647
)
23
Data Source:
HPRD
(two hybrid)
SUFU
RNF19A
Gene Name
suppressor of fused homolog (Drosophila)
ring finger protein 19A, RBR E3 ubiquitin protein ligase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Primary Cilium
Ciliary Tip
Ciliary Base
Cytoplasm
Centrosome
Integral Component Of Membrane
Molecular Function
Transcription Corepressor Activity
Signal Transducer Activity
Protein Binding
Beta-catenin Binding
Transcription Factor Binding
Protein Kinase Binding
Transcription Factor Binding
Zinc Ion Binding
Ligase Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Skeletal System Development
Neural Tube Closure
Heart Looping
Regulation Of Transcription, DNA-templated
Proteolysis
Signal Transduction
Multicellular Organismal Development
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification
Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification
Negative Regulation Of Transcription Factor Import Into Nucleus
Cytoplasmic Sequestering Of Transcription Factor
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Skin Development
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Smoothened Signaling Pathway
Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Microtubule Cytoskeleton Organization
Protein Ubiquitination
Pathways
Hedgehog 'off' state
Hedgehog 'on' state
Signaling by Hedgehog
Degradation of GLI1 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Degradation of GLI2 by the proteasome
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Atrioventricular conduction (
21041692
)
Protein-Protein Interactions
26 interactors:
BTRC
GLI1
GLI2
GLI3
GLIS3
HDX
HMGA1
HNRNPA1
LAMTOR3
LGALS3
MID1IP1
NCOA3
PEX26
PIAS1
QPRT
RBPJ
RCN3
RNF19A
SAP18
SETDB1
STK36
ZNF219
ZNF263
ZNF446
ZNF747
ZNF764
16 interactors:
C11orf58
CASR
ILK
MAP3K7
NUDT21
RPS6KA5
SNCAIP
SOD1
SUFU
TUBG1
TUBG2
UBE2E2
UBE2L3
UBE2L6
VCP
ZAK
Entrez ID
51684
25897
HPRD ID
06124
06176
Ensembl ID
ENSG00000107882
ENSG00000034677
Uniprot IDs
Q9UMX1
Q9NV58
PDB IDs
1M1L
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Smoothened Signaling Pathway
Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Notochord Regression
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Mammary Gland Morphogenesis
Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification
Tube Morphogenesis
Smoothened Signaling Pathway
Smoothened Signaling Pathway Involved In Regulation Of Cerebellar Granule Cell Precursor Cell Proliferation
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Ventral Midline Development
Gland Development
Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Organ Formation
Proximal/distal Pattern Formation
Cerebellar Purkinje Cell-granule Cell Precursor Cell Signaling Involved In Regulation Of Granule Cell Precursor Cell Proliferation
Pituitary Gland Development
Gland Morphogenesis
Positive Regulation Of Neural Precursor Cell Proliferation
Mammary Gland Development
Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation
Positive Regulation Of Protein Modification Process
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Cellular Protein Metabolic Process
ISG15-protein Conjugation
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of MAP Kinase Activity
MAPK Cascade
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Transferase Activity
JNK Cascade
Cellular Response To Stress
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Catalytic Activity
Signal Transduction By Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of MAP Kinase Activity
Positive Regulation Of Protein Phosphorylation
Microtubule Nucleation
Epithelial Tube Morphogenesis
Protein K11-linked Ubiquitination
Cellular Response To Organic Substance
Activation Of MAPK Activity
Response To Stress
Microtubule Polymerization
Tube Morphogenesis
Positive Regulation Of MAPK Cascade
Positive Regulation Of Phosphorylation
Positive Regulation Of Protein Kinase Activity
Vasodilation
Positive Regulation Of Kinase Activity
Cytoplasmic Microtubule Organization
Morphogenesis Of An Epithelium
Microtubule Polymerization Or Depolymerization
Regulation Of Cytokine Production
Protein Complex Assembly
Cell Cycle Process
Myelination In Peripheral Nervous System
Regulation Of Catalytic Activity
Protein Ubiquitination
Cellular Protein Modification Process
Regulation Of Protein Phosphorylation
Schwann Cell Development
Epithelium Development
Toll-like Receptor 5 Signaling Pathway
Protein Modification By Small Protein Conjugation
Toll-like Receptor 10 Signaling Pathway
Regulation Of MAPK Cascade
Cell Cycle Phase Transition
Response To Organic Substance
Tagcloud
?
beta1
blots
cck
colorectal
constructed
counting
enhances
gli1
hedgehog
hh
ht29
infecting
integrin
interference
invasion
itgb1
kit
lentiviral
lentivirus
malignancies
migrating
rnai
shh
sonic
transwell
unrelated
vectors
xenografted
xenografting
Tagcloud (Difference)
?
beta1
blots
cck
colorectal
constructed
counting
enhances
gli1
hedgehog
hh
ht29
infecting
integrin
interference
invasion
itgb1
kit
lentiviral
lentivirus
malignancies
migrating
rnai
shh
sonic
transwell
unrelated
vectors
xenografted
xenografting
Tagcloud (Intersection)
?