MID2 and CEP57L1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MID2	CEP57L1
Gene Name		midline 2	centrosomal protein 57kDa-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Extracellular Vesicular Exosome	Cellular_component Cytoplasm Microtubule Organizing Center Microtubule
	Molecular Function	Microtubule Binding Zinc Ion Binding Ligase Activity Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding	Molecular_function Microtubule Binding Identical Protein Binding Gamma-tubulin Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Viral Transcription Protein Localization To Microtubule Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell	Biological_process Microtubule Anchoring
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		108 interactors: ADAMTSL4 AEN AQP1 ATRIP BCL6B BRCA1 BRMS1L BYSL C19orf66 CALCOCO2 CBX8 CCDC120 CCDC42 CCHCR1 CEP57L1 CHD2 CTSZ DCX DGCR6 DGCR6L DIEXF DMRT3 DYDC1 FAM107A FAM161A FAM214A FAM90A1 FARS2 FBF1 FBXL18 FRMD6 GFI1B GMCL1 GOLGA2 GORASP2 HOXB9 IGBP1 ISCU JOSD1 KIAA1683 KIF1A KIFC3 LENG1 LGALS14 LGALS8 MAGOHB METTL17 MFAP1 MID1 MID1IP1 MOS MVP NR1D2 NXF1 OTUB2 PPP1R18 PRPF31 PSMA1 PTCD2 RCOR3 RPH3AL RPP25L RUNX1T1 SCNM1 SDCBP SLC25A48 SLC25A6 SNAI1 SNAP47 SPATA24 SPG21 SPRY2 STX11 SYT17 TCEA2 TCEB3 THAP7 TOP3B TRIM27 TRIM29 TRIM32 TRIM42 TRIM54 TRPV6 TSGA10 UBE2D1 UBE2D4 UBE2E2 UBE2E3 UBE2U UBTD1 UNC45A UTP23 WT1-AS ZBTB24 ZC2HC1C ZFYVE21 ZGPAT ZNF165 ZNF24 ZNF250 ZNF417 ZNF440 ZNF564 ZNF587 ZNF785 ZNF792 ZSCAN12	69 interactors: ALOX5 AP1M1 ARNT2 BRCA1 BYSL C6orf165 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 DISC1 DYDC1 EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LENG1 LMO3 LZTS2 MAGEA1 MAGEA2B MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NUP62 PKN1 PNMA5 PPL RAD51D RINT1 ROPN1 SNAP47 SNAPC3 SPERT TAB3 TCEB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB
Entrez ID		11043	285753
HPRD ID		02191	10792
Ensembl ID			ENSG00000183137
Uniprot IDs		Q9UJV3	G5E992 Q8IYX8
PDB IDs		2DJA 2DMK
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Protein Polyubiquitination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Protein K63-linked Ubiquitination Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Protein K48-linked Ubiquitination Negative Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Cellular Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Metabolic Process Protein K11-linked Ubiquitination Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA Cellular Metabolic Process Negative Regulation Of Microtubule Depolymerization Protein K6-linked Ubiquitination Regulation Of Microtubule-based Process Ribosomal Small Subunit Biogenesis Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Microtubule Polymerization Or Depolymerization Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Transferase Activity Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Microtubule Cytoskeleton Organization Regulation Of Viral Transcription Regulation Of Histone H3-K4 Methylation Regulation Of Microtubule Polymerization Or Depolymerization	Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Organelle Organization Microtubule-based Process Regulation Of Stress-activated MAPK Cascade Regulation Of MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Cell Cycle Regulation Of Signal Transduction Microtubule Severing Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Intracellular Signal Transduction Microtubule Cytoskeleton Organization Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Cellular Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Spindle Assembly Positive Regulation Of Protein Modification Process Regulation Of JUN Kinase Activity Double-strand Break Repair Via Homologous Recombination Recombinational Repair JNK Cascade Negative Regulation Of Protein Acetylation Centrosome Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of MAP Kinase Activity Mitotic Cell Cycle Positive Regulation Of Transferase Activity Microtubule Organizing Center Organization Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Process Cell Differentiation Involved In Embryonic Placenta Development Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Spliceosomal Complex Disassembly Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
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