TDP2 and SNX13

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TDP2	SNX13
Gene Name		tyrosyl-DNA phosphodiesterase 2	sorting nexin 13
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm PML Body Intercellular Bridge	Early Endosome Early Endosome Membrane
	Molecular Function	Magnesium Ion Binding Single-stranded DNA Binding Transcription Corepressor Activity Nuclease Activity Protein Binding Manganese Ion Binding Tyrosyl-RNA Phosphodiesterase Activity 5'-tyrosyl-DNA Phosphodiesterase Activity	Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding
	Biological Process	Double-strand Break Repair Cell Surface Receptor Signaling Pathway Nucleic Acid Phosphodiester Bond Hydrolysis Negative Regulation Of Nucleic Acid-templated Transcription	Intracellular Protein Transport Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: AKAP9 ATP5G2 ATXN1 C2orf88 CD40 DLX3 EPS8 ETS1 ETS2 FLI1 JAM2 MAPK6 PSEN1 RAB11A SKIL SMAD3 SNX13 SRPK2 SUMO1 SUMO2 SUMO3 TAP1 TNFRSF1B TNFRSF8 TRAF2 TRAF3 TRAF5 TRAF6 UBE2I	5 interactors: G6PC GNAS KLF15 NR1I3 TDP2
Entrez ID		51567	23161
HPRD ID		05771	09418
Ensembl ID		ENSG00000111802	ENSG00000071189
Uniprot IDs		O95551	Q86XC4 Q9Y5W8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Immune System Process Positive Regulation Of Cellular Metabolic Process Protein Sumoylation Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cellular Protein Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Apoptotic Process Positive Regulation Of Cell Death Regulation Of Metabolic Process Regulation Of Immunoglobulin Secretion Regulation Of Cell Death Regulation Of Proteolysis Regulation Of Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of RNA Metabolic Process Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Signal Transduction PML Body Organization Immune Response Regulation Of Binding Response To Organic Substance Response To Stimulus Response To Cytokine Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Intracellular Signal Transduction Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cytokine Production Negative Regulation Of RNA Biosynthetic Process	Glucose Transport Hexose Transport Post-embryonic Body Morphogenesis Multicellular Organism Growth Carbohydrate Transport Energy Reserve Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Glucose-6-phosphate Transport Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Peptide Urate Metabolic Process Phosphorylated Carbohydrate Dephosphorylation Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Cellular Response To Organic Cyclic Compound Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Prostaglandin E Stimulus Response To Parathyroid Hormone Generation Of Precursor Metabolites And Energy Cellular Response To Lipid Positive Regulation Of CAMP-mediated Signaling Regulation Of Metabolic Process Adrenergic Receptor Signaling Pathway Glomerular Visceral Epithelial Cell Differentiation Glycogen Catabolic Process Hair Follicle Placode Formation Cellular Response To Organonitrogen Compound Cardiac Muscle Hypertrophy In Response To Stress Response To Peptide Cellular Response To Prostaglandin Stimulus Response To Prostaglandin E Growth Cellular Response To Organic Substance Negative Regulation Of Multicellular Organism Growth Polysaccharide Catabolic Process Regulation Of CAMP-mediated Signaling CAMP Biosynthetic Process Negative Regulation Of Peptidyl-lysine Acetylation Response To Food Response To Stimulus Negative Regulation Of Protein Acetylation Positive Regulation Of Osteoclast Differentiation Cardiac Muscle Hypertrophy Cellular Response To Catecholamine Stimulus Cellular Response To Hormone Stimulus Nucleobase-containing Compound Metabolic Process Muscle Hypertrophy
Tagcloud ?		accrued akin ape2 aprataxin aptx apurinic arsenal cleansing ctip endonucleases environ fen1 mre11 mutagen nucleolytic phosphodiesterases pnk polbeta polynucleotide rad50 rddr splintered ssbs tailor tdp1 termini topoisomerases toxicants transactions
Tagcloud (Difference) ?		accrued akin ape2 aprataxin aptx apurinic arsenal cleansing ctip endonucleases environ fen1 mre11 mutagen nucleolytic phosphodiesterases pnk polbeta polynucleotide rad50 rddr splintered ssbs tailor tdp1 termini topoisomerases toxicants transactions
Tagcloud (Intersection) ?