SNX13 and G6PC1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SNX13	G6PC1
Description		sorting nexin 13	glucose-6-phosphatase catalytic subunit 1
Image
GO Annotations	Cellular Component	Endosome Early Endosome Membrane Early Endosome Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Lipid Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding	Glucose-6-phosphatase Activity Protein Binding Phosphotransferase Activity, Alcohol Group As Acceptor Hydrolase Activity Phosphate Ion Binding
	Biological Process	Intracellular Protein Transport Negative Regulation Of Signal Transduction Protein Transport Positive Regulation Of GTPase Activity	Glycogen Metabolic Process Glycogen Catabolic Process Gluconeogenesis Triglyceride Metabolic Process Steroid Metabolic Process Response To Carbohydrate Regulation Of Gene Expression Glucose-6-phosphate Transport Response To Nutrient Levels Response To Food Response To Insulin Cellular Response To Insulin Stimulus Multicellular Organism Growth Glucose Homeostasis Cholesterol Homeostasis Urate Metabolic Process Chemical Homeostasis Glucose 6-phosphate Metabolic Process Lipid Homeostasis Response To Caloric Restriction Response To Resveratrol
Pathways			Glycogen storage disease type Ia (G6PC) Gluconeogenesis FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Adiponectin levels ( 31178129) Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Chronic widespread musculoskeletal pain ( 33331911) Creatine kinase levels ( 29403010) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol ( 30275531 24097068) HDL cholesterol levels ( 30698716 28334899 32203549) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549) Lactate dehydrogenase levels ( 29403010) LDL cholesterol levels x long total sleep time interaction (1df test) ( 31719535) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Metabolic syndrome ( 31589552) Neutrophil count ( 32888494) Parkinson's disease progression (composite) ( 33111402) Severe influenza A (H1N1) infection ( 26379185) Tea consumption ( 31046077) Triglyceride levels ( 32154731 32203549) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels in HIV infection ( 33109212) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		5 interacting genes: G6PC1 GNAS KLF15 NR1I3 TDP2	4 interacting genes: CDH16 FOXO1 NSL1 SNX13
Entrez ID		23161	2538
HPRD ID		09418	01983
Ensembl ID		ENSG00000071189	ENSG00000131482
Uniprot IDs		B3KN60 Q86XC4 Q9NSH0 Q9Y5W8	P35575
PDB IDs		7WF6	9J7U 9J7V
Enriched GO Terms of Interacting Partners?		Cellular Response To Peptide Hormone Stimulus Response To Peptide Hormone Cellular Response To Hormone Stimulus 5'-tyrosyl-DNA Phosphodiesterase Activity Tyrosyl-RNA Phosphodiesterase Activity Tyrosyl-DNA Phosphodiesterase Activity Response To Hormone Carbohydrate Homeostasis Glucose Homeostasis Response To Resveratrol Glucose-6-phosphatase Activity Cellular Response To Oxygen-containing Compound Response To Insulin Chemical Homeostasis Glucose-6-phosphate Transport Hair Follicle Placode Formation Mu-type Opioid Receptor Binding Corticotropin-releasing Hormone Receptor 1 Binding Adenylate Cyclase Activator Activity Adenylate Cyclase-activating Serotonin Receptor Signaling Pathway Adenylate Cyclase Regulator Activity Negative Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Protein Acetylation Beta-2 Adrenergic Receptor Binding D1 Dopamine Receptor Binding Developmental Growth Glycogen Catabolic Process Urate Metabolic Process Response To Stilbenoid Phosphotransferase Activity, Alcohol Group As Acceptor Phosphate Ion Binding Response To Stress Glucose 6-phosphate Metabolic Process Homeostatic Process Regulation Of Metabolic Process Response To Caloric Restriction Cellular Response To Acidic PH Guanyl Nucleotide Binding Vascular Endothelial Cell Response To Fluid Shear Stress Response To Catecholamine Renal Water Homeostasis G-protein Beta/gamma-subunit Complex Binding Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Lyase Activity Cellular Response To Glucagon Stimulus Cellular Response To Prostaglandin E Stimulus Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Regulation Of Skeletal Muscle Contraction Positive Regulation Of Adenylate Cyclase Activity
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