ANKRD23 and CLIC3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ANKRD23	CLIC3
Name		ankyrin repeat domain 23	chloride intracellular channel 3
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intercalated Disc Actin Cytoskeleton Myofibril I Band	Extracellular Region Nucleus Cytoplasm Plasma Membrane Membrane Nuclear Body Extracellular Matrix Monoatomic Ion Channel Complex Chloride Channel Complex Extracellular Exosome
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Titin Binding	Chloride Channel Activity Protein Binding Oxidoreductase Activity Protein-disulfide Reductase (glutathione) Activity
	Biological Process	Fatty Acid Metabolic Process Response To Mechanical Stimulus Response To Muscle Stretch Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Sarcomere Organization	Monoatomic Ion Transport Chloride Transport Signal Transduction Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport Positive Regulation Of Sprouting Angiogenesis
GWAS		Bipolar disorder ( 31043756 )	No GWAS studies recorded
Interacting Genes		20 interacting genes: CCDC102B CCDC57 CDCA7L CLIC3 ENKD1 FAM90A1 GRB2 HOOK1 HRAS IQUB KDM1A KIFC3 MIPOL1 MYPN NAP1L1 PIBF1 POLR3C SMARCD1 TRIM41 TTN	35 interacting genes: AGR2 ALX1 ANKRD23 ANKRD55 APP CIMIP2B DDIT4L DNM1 EFHC2 GLYR1 INCA1 KATNBL1 KRT85 KRTAP13-3 LELP1 MAPK15 MBD3L1 MECOM MIA3 MSX2 POT1 PROSER2 SCML4 SPMIP4 SPMIP6 STMN3 TBC1D3 TBC1D3C TBC1D3K TEPSIN TLE5 VPS4A ZBTB42 ZC2HC1C ZNF620
Entrez ID		200539	9022
HPRD ID		12462	05941
Ensembl ID		ENSG00000163126	ENSG00000169583
Uniprot IDs		Q86SG2	O95833
PDB IDs		Not available	3FY7 3KJY
GO Terms Enriched among Interactors		Cytoskeleton Organization Centrosome Cellular Response To Ionizing Radiation Schwann Cell Development Microtubule-based Process Muscle Alpha-actinin Binding Cilium Assembly Positive Regulation Of Multicellular Organismal Process Cilium Organization I Band Cellular Response To Gamma Radiation Response To Ionizing Radiation Plasma Membrane Bounded Cell Projection Assembly	None