ANKRD23 and MYPN

Number of citations: 0 (PubMedID 14583192)
Data Source: HPRD (two hybrid)

		ANKRD23	MYPN
Name		ankyrin repeat domain 23	myopalladin
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intercalated Disc Actin Cytoskeleton Myofibril I Band	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Sarcomere Z Disc Axon I Band
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Titin Binding	Actin Binding Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Muscle Alpha-actinin Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Fatty Acid Metabolic Process Response To Mechanical Stimulus Response To Muscle Stretch Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Sarcomere Organization	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Sarcomere Organization Dendrite Self-avoidance
GWAS		Bipolar disorder ( 31043756 )	Appendicular lean mass ( 33097823 ) Atrial fibrillation ( 30061737 ) Chronic kidney disease ( 31152163 ) Coffee consumption ( 31046077 ) Creatine kinase levels ( 29403010 ) Creatinine levels ( 29403010 ) Estimated glomerular filtration rate ( 30604766 31451708 31152163 31015462 ) Estimated glomerular filtration rate in non-diabetics ( 31451708 ) FEV1 ( 30804560 ) Glomerular filtration rate ( 29403010 ) Height ( 25282103 ) Hip circumference adjusted for BMI ( 34021172 ) Lung function (FVC) ( 30804560 28166213 ) Optic nerve measurement (disc area) ( 20395239 ) Peak expiratory flow ( 30804560 ) Psoriasis ( 25854761 )
Interacting Genes		20 interacting genes: CCDC102B CCDC57 CDCA7L CLIC3 ENKD1 FAM90A1 GRB2 HOOK1 HRAS IQUB KDM1A KIFC3 MIPOL1 MYPN NAP1L1 PIBF1 POLR3C SMARCD1 TRIM41 TTN	8 interacting genes: ACTN2 ACTN3 ANKRD1 ANKRD23 NEB NEBL PDLIM3 TTN
Entrez ID		200539	84665
HPRD ID		12462	10536
Ensembl ID		ENSG00000163126	ENSG00000138347
Uniprot IDs		Q86SG2	A0A087WX60 Q86TC9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Cytoskeleton Organization Centrosome Cellular Response To Ionizing Radiation Schwann Cell Development Microtubule-based Process Muscle Alpha-actinin Binding Cilium Assembly Positive Regulation Of Multicellular Organismal Process Cilium Organization I Band Cellular Response To Gamma Radiation Response To Ionizing Radiation Plasma Membrane Bounded Cell Projection Assembly	Structural Constituent Of Muscle Z Disc I Band Actin Cytoskeleton Actin Filament Binding Cytoskeletal Protein Binding Titin Binding Response To Muscle Stretch Actin Cytoskeleton Organization Actin Binding Actin Filament-based Process Cardiac Muscle Thin Filament Assembly Sarcomere Organization Myofibril Sarcomere Actin Filament Organization Muscle Cell Development Actomyosin Structure Organization Muscle Alpha-actinin Binding Pseudopodium Cytoskeleton Organization Supramolecular Fiber Organization Focal Adhesion Assembly Response To Mechanical Stimulus Cell-substrate Junction Assembly Cardiac Muscle Cell Development Cell-substrate Junction Organization Cardiac Cell Development Cortical Actin Cytoskeleton Cardiac Muscle Tissue Morphogenesis Regulation Of Actin Cytoskeleton Organization Actin Filament Uncapping Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Striated Muscle Cell Development Muscle Tissue Morphogenesis Regulation Of Actin Filament-based Process Actin Filament Stress Fiber Titin Z Domain Binding Cytoplasm Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Sarcomerogenesis Extracellular Exosome Phospholipase C-activating Angiotensin-activated Signaling Pathway Positive Regulation Of Bone Mineralization Involved In Bone Maturation Skeletal Muscle Myosin Thick Filament Assembly Regulation Of Cytoskeleton Organization