ARL6IP4 and RNF41

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ARL6IP4	RNF41
Gene Name		ADP-ribosylation factor-like 6 interacting protein 4	ring finger protein 41, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Nuclear Speck	Cytosol
	Molecular Function	Protein Binding Poly(A) RNA Binding	Ubiquitin-protein Transferase Activity Erythropoietin Receptor Binding Interleukin-3 Receptor Binding Protein Binding Zinc Ion Binding Acid-amino Acid Ligase Activity Ral GTPase Binding Protein Tag Ubiquitin Protein Ligase Activity
	Biological Process	MRNA Processing RNA Splicing	Protein Polyubiquitination Autophagy Negative Regulation Of Cell Proliferation Proteasomal Protein Catabolic Process Negative Regulation Of Cell Migration Regulation Of MAPK Cascade Regulation Of Lymphocyte Differentiation Regulation Of Myeloid Cell Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Autoubiquitination Regulation Of Protein Kinase B Signaling Extrinsic Apoptotic Signaling Pathway Regulation Of Establishment Of Cell Polarity Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Signaling by ERBB2 Downregulation of ERBB2:ERBB3 signaling Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ARL6 CSNK2A1 ETS1 FOS IKBKG RBM39 RNF41 SRPK1 SRPK2 SRSF11 THAP1	26 interactors: ADRB2 APP ARL6IP4 ASB6 BIRC6 C1orf109 ERBB3 ERBB4 HOMER2 ISCA2 LEPR LZTS2 MARK2 MNAT1 RFC4 RNF166 TRIM32 TRIM8 TSG101 TTC1 UBE2D3 UBE2K UBE2U UBE2Z USP8 VPS52
Entrez ID		51329	10193
HPRD ID		09640	11520
Ensembl ID		ENSG00000182196
Uniprot IDs		B3V0L0 B3V0L1 Q66PJ3	Q9H4P4
PDB IDs			2FZP 2GWF
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Regulation Of RNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Heterocycle Metabolic Process Nucleus Organization Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process MRNA Processing Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Viral Genome Replication Regulation Of Myeloid Cell Differentiation Nitrogen Compound Metabolic Process MRNA Metabolic Process RNA Processing Immune Response Negative Regulation Of Viral Genome Replication Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cellular Macromolecule Biosynthetic Process Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity TRIF-dependent Toll-like Receptor Signaling Pathway Macromolecule Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Viral Genome Replication Nuclear Speck Organization MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Viral Process Negative Regulation Of Viral Process Positive Regulation Of Myeloid Cell Differentiation Regulation Of Cell Cycle Toll-like Receptor 4 Signaling Pathway Regulation Of MRNA Processing Regulation Of Metabolic Process Phosphorylation Intracellular Signal Transduction Intermembrane Transport Regulation Of RNA Splicing Cellular Response To Reactive Oxygen Species	Cellular Protein Modification Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Metabolic Process Protein Polyubiquitination Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Catabolic Process Regulation Of Protein Metabolic Process Protein Catabolic Process Apoptotic Process Programmed Cell Death Regulation Of Viral Transcription Cell Death Death Cellular Response To Stimulus Negative Regulation Of Viral Release From Host Cell Regulation Of Kinase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Proteasomal Protein Catabolic Process Regulation Of Signal Transduction Negative Regulation Of Viral Transcription Response To Stress Regulation Of Viral Release From Host Cell Catabolic Process Response To Stimulus Cellular Metabolic Process Regulation Of Growth Regulation Of Signaling Cell Cycle Process Regulation Of Cell Proliferation Regulation Of Proteolysis Cell Surface Receptor Signaling Pathway Regulation Of Viral Process Regulation Of Protein Phosphorylation Signal Transduction Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Regulation Of Protein Kinase Activity Mitotic Cell Cycle Cell Division Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Signaling Positive Regulation Of Intracellular Signal Transduction
Tagcloud ?			aforementioned balanced cytokine destabilizes determines deubiquitylating dub e3 ectodomain ectopic escrt explains finger identifies indirectly internalization lif lysosomal matches reciprocal recycling redistributes shedding sorted stabilizes steady trafficking ubiquitylates usp8
Tagcloud (Difference) ?			aforementioned balanced cytokine destabilizes determines deubiquitylating dub e3 ectodomain ectopic escrt explains finger identifies indirectly internalization lif lysosomal matches reciprocal recycling redistributes shedding sorted stabilizes steady trafficking ubiquitylates usp8
Tagcloud (Intersection) ?