RNF41 and ARL6IP4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RNF41	ARL6IP4
Gene Name		ring finger protein 41, E3 ubiquitin protein ligase	ADP-ribosylation factor-like 6 interacting protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Nucleolus Nuclear Speck
	Molecular Function	Ubiquitin-protein Transferase Activity Erythropoietin Receptor Binding Interleukin-3 Receptor Binding Protein Binding Zinc Ion Binding Acid-amino Acid Ligase Activity Ral GTPase Binding Protein Tag Ubiquitin Protein Ligase Activity	Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Polyubiquitination Autophagy Negative Regulation Of Cell Proliferation Proteasomal Protein Catabolic Process Negative Regulation Of Cell Migration Regulation Of MAPK Cascade Regulation Of Lymphocyte Differentiation Regulation Of Myeloid Cell Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Autoubiquitination Regulation Of Protein Kinase B Signaling Extrinsic Apoptotic Signaling Pathway Regulation Of Establishment Of Cell Polarity Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process	MRNA Processing RNA Splicing
Pathways		Signaling by ERBB2 Downregulation of ERBB2:ERBB3 signaling Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: ADRB2 APP ARL6IP4 ASB6 BIRC6 C1orf109 ERBB3 ERBB4 HOMER2 ISCA2 LEPR LZTS2 MARK2 MNAT1 RFC4 RNF166 TRIM32 TRIM8 TSG101 TTC1 UBE2D3 UBE2K UBE2U UBE2Z USP8 VPS52	11 interactors: ARL6 CSNK2A1 ETS1 FOS IKBKG RBM39 RNF41 SRPK1 SRPK2 SRSF11 THAP1
Entrez ID		10193	51329
HPRD ID		11520	09640
Ensembl ID			ENSG00000182196
Uniprot IDs		Q9H4P4	B3V0L0 B3V0L1 Q66PJ3
PDB IDs		2FZP 2GWF
Enriched GO Terms of Interacting Partners?		Cellular Protein Modification Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Metabolic Process Protein Polyubiquitination Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Catabolic Process Regulation Of Protein Metabolic Process Protein Catabolic Process Apoptotic Process Programmed Cell Death Regulation Of Viral Transcription Cell Death Death Cellular Response To Stimulus Negative Regulation Of Viral Release From Host Cell Regulation Of Kinase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Proteasomal Protein Catabolic Process Regulation Of Signal Transduction Negative Regulation Of Viral Transcription Response To Stress Regulation Of Viral Release From Host Cell Catabolic Process Response To Stimulus Cellular Metabolic Process Regulation Of Growth Regulation Of Signaling Cell Cycle Process Regulation Of Cell Proliferation Regulation Of Proteolysis Cell Surface Receptor Signaling Pathway Regulation Of Viral Process Regulation Of Protein Phosphorylation Signal Transduction Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Regulation Of Protein Kinase Activity Mitotic Cell Cycle Cell Division Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Signaling Positive Regulation Of Intracellular Signal Transduction	RNA Metabolic Process Gene Expression Regulation Of RNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Heterocycle Metabolic Process Nucleus Organization Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process MRNA Processing Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Viral Genome Replication Regulation Of Myeloid Cell Differentiation Nitrogen Compound Metabolic Process MRNA Metabolic Process RNA Processing Immune Response Negative Regulation Of Viral Genome Replication Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cellular Macromolecule Biosynthetic Process Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity TRIF-dependent Toll-like Receptor Signaling Pathway Macromolecule Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Viral Genome Replication Nuclear Speck Organization MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Viral Process Negative Regulation Of Viral Process Positive Regulation Of Myeloid Cell Differentiation Regulation Of Cell Cycle Toll-like Receptor 4 Signaling Pathway Regulation Of MRNA Processing Regulation Of Metabolic Process Phosphorylation Intracellular Signal Transduction Intermembrane Transport Regulation Of RNA Splicing Cellular Response To Reactive Oxygen Species
Tagcloud ?		aforementioned balanced cytokine destabilizes determines deubiquitylating dub e3 ectodomain ectopic escrt explains finger identifies indirectly internalization lif lysosomal matches reciprocal recycling redistributes shedding sorted stabilizes steady trafficking ubiquitylates usp8
Tagcloud (Difference) ?		aforementioned balanced cytokine destabilizes determines deubiquitylating dub e3 ectodomain ectopic escrt explains finger identifies indirectly internalization lif lysosomal matches reciprocal recycling redistributes shedding sorted stabilizes steady trafficking ubiquitylates usp8
Tagcloud (Intersection) ?