RNF41 and C1orf109

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RNF41	C1orf109
Gene Name		ring finger protein 41, E3 ubiquitin protein ligase	chromosome 1 open reading frame 109
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Erythropoietin Receptor Binding Interleukin-3 Receptor Binding Protein Binding Zinc Ion Binding Acid-amino Acid Ligase Activity Ral GTPase Binding Protein Tag Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Autophagy Negative Regulation Of Cell Proliferation Proteasomal Protein Catabolic Process Negative Regulation Of Cell Migration Regulation Of MAPK Cascade Regulation Of Lymphocyte Differentiation Regulation Of Myeloid Cell Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Autoubiquitination Regulation Of Protein Kinase B Signaling Extrinsic Apoptotic Signaling Pathway Regulation Of Establishment Of Cell Polarity Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Signaling by ERBB2 Downregulation of ERBB2:ERBB3 signaling Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: ADRB2 APP ARL6IP4 ASB6 BIRC6 C1orf109 ERBB3 ERBB4 HOMER2 ISCA2 LEPR LZTS2 MARK2 MNAT1 RFC4 RNF166 TRIM32 TRIM8 TSG101 TTC1 UBE2D3 UBE2K UBE2U UBE2Z USP8 VPS52	44 interactors: AES C1orf94 CCDC36 CEP55 CINP CRX CSNK2A1 GOLGA2 IKZF1 IKZF3 KATNAL1 KIFC3 KRT13 KRT19 KRT31 KRT40 LDOC1 LZTS2 MEOX2 MKRN2 MTUS2 NECAB2 PDE4DIP PHC2 PLK4 PPP1R12C REL RINT1 RNF41 SDCBP SPAG5 SPERT STX11 TADA2A TCF12 TCF4 TFIP11 TRAF1 TRIM42 TRIM54 USHBP1 VPS52 ZBED1 ZNF398
Entrez ID		10193	54955
HPRD ID		11520	07918
Ensembl ID			ENSG00000116922
Uniprot IDs		Q9H4P4	B4DRQ5 Q9NX04
PDB IDs		2FZP 2GWF
Enriched GO Terms of Interacting Partners?		Cellular Protein Modification Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Metabolic Process Protein Polyubiquitination Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Catabolic Process Regulation Of Protein Metabolic Process Protein Catabolic Process Apoptotic Process Programmed Cell Death Regulation Of Viral Transcription Cell Death Death Cellular Response To Stimulus Negative Regulation Of Viral Release From Host Cell Regulation Of Kinase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Proteasomal Protein Catabolic Process Regulation Of Signal Transduction Negative Regulation Of Viral Transcription Response To Stress Regulation Of Viral Release From Host Cell Catabolic Process Response To Stimulus Cellular Metabolic Process Regulation Of Growth Regulation Of Signaling Cell Cycle Process Regulation Of Cell Proliferation Regulation Of Proteolysis Cell Surface Receptor Signaling Pathway Regulation Of Viral Process Regulation Of Protein Phosphorylation Signal Transduction Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Regulation Of Protein Kinase Activity Mitotic Cell Cycle Cell Division Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Signaling Positive Regulation Of Intracellular Signal Transduction	Cell Cycle Mitotic Cell Cycle Microtubule Severing Developmental Process Transcription, DNA-templated RNA Biosynthetic Process Mitotic Cell Cycle Process Multicellular Organismal Development Anatomical Structure Development Cell Cycle Process Positive Regulation Of Organelle Assembly Wnt Signaling Pathway Organ Development Microtubule-based Process Regulation Of Wnt Signaling Pathway Cytoskeleton Organization Organelle Organization Regulation Of Microtubule Cytoskeleton Organization System Development Cell Differentiation Involved In Embryonic Placenta Development RNA Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Binding Transcription From RNA Polymerase II Promoter Regulation Of Lymphocyte Differentiation Regulation Of Transcription, DNA-templated Positive Regulation Of Neutrophil Differentiation Spliceosomal Complex Disassembly Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Positive Regulation Of Photoreceptor Cell Differentiation Regulation Of Organelle Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of Microtubule-based Process Regulation Of RNA Biosynthetic Process Embryonic Digestive Tract Development Regulation Of RNA Metabolic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Tissue Development Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Division Negative Regulation Of Protein Binding Catenin Import Into Nucleus Positive Regulation Of Centriole Replication Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization
Tagcloud ?		aforementioned balanced cytokine destabilizes determines deubiquitylating dub e3 ectodomain ectopic escrt explains finger identifies indirectly internalization lif lysosomal matches reciprocal recycling redistributes shedding sorted stabilizes steady trafficking ubiquitylates usp8
Tagcloud (Difference) ?		aforementioned balanced cytokine destabilizes determines deubiquitylating dub e3 ectodomain ectopic escrt explains finger identifies indirectly internalization lif lysosomal matches reciprocal recycling redistributes shedding sorted stabilizes steady trafficking ubiquitylates usp8
Tagcloud (Intersection) ?