ARL6IP4 and SRSF11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ARL6IP4	SRSF11
Description		ARF like GTPase 6 interacting protein 4	serine and arginine rich splicing factor 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Nuclear Speck	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Processing RNA Splicing	MRNA Processing RNA Splicing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 23974872 25056061 29483656) Tourette syndrome ( 30818990)
Interacting Genes		21 interacting genes: AP1M1 ARL6 C1orf35 CEBPA CSNK2A1 ETS1 FOS IKBKG KRCC1 NKAPD1 NKAPL RBM39 RNF41 SREK1 SRPK2 SRRM4 SRSF11 THAP1 TRIM55 TRIM63 WEE2-AS1	33 interacting genes: ARL6IP4 ATP5F1D CDK6 CSNK2A1 DACH1 DDOST DUSP29 ETS1 GATC HNRNPLL HYI LNX2 MDM2 MEOX2 OGT PAK5 PAX6 PIN1 PUF60 RAB2B RNPS1 SDCBP SREK1 SRPK2 SRRM4 SRSF1 SRSF2 TANK THAP11 TOP1 U2AF2 ZC3HAV1 ZNF385C
Entrez ID		51329	9295
HPRD ID		09640	03599
Ensembl ID		ENSG00000182196	ENSG00000116754
Uniprot IDs		A0A0C4DG62 A0A0C4DH18 A0A8C8KBE9 F8WCT1 F8WEP2 Q66PJ3	Q05519 Q5T757 Q5T760
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Identical Protein Binding Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing MRNA Processing Nuclear Body Organization Regulation Of MRNA Splicing, Via Spliceosome	Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Nuclear Speck Regulation Of MRNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Splicing Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Nucleic Acid Binding Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nucleic Acid Metabolic Process RNA Binding Nucleus Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Splicing Regulation Of Cell Motility Regulation Of Locomotion Protein Binding Nuclear Body Organization Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome Chromatin DNA Binding Negative Regulation Of Macromolecule Metabolic Process Exon-exon Junction Complex RNA Splicing, Via Transesterification Reactions Positive Regulation Of Type I Interferon Production Sin3-type Complex Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Cell Cycle Protein Serine/threonine Kinase Activity Negative Regulation Of MRNA Metabolic Process Alternative MRNA Splicing, Via Spliceosome
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