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ECSIT and IMMT
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ECSIT
IMMT
Description
ECSIT signaling integrator
inner membrane mitochondrial protein
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Cytosol
SAM Complex
Mitochondrion
Mitochondrial Envelope
Mitochondrial Inner Membrane
Mitochondrial Intermembrane Space
Membrane
Mitochondrial Crista Junction
MICOS Complex
MIB Complex
Molecular Function
Protein Binding
Molecular Adaptor Activity
RNA Binding
Protein Binding
Biological Process
Immune System Process
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Mitochondrial Respiratory Chain Complex I Assembly
Toll-like Receptor 4 Signaling Pathway
Non-canonical NF-kappaB Signal Transduction
Innate Immune Response
Regulation Of Oxidoreductase Activity
Regulation Of Protein Complex Stability
Inner Mitochondrial Membrane Organization
Cristae Formation
Mitochondrial Calcium Ion Homeostasis
Neuron Cellular Homeostasis
Pathways
MyD88:MAL(TIRAP) cascade initiated on plasma membrane
Complex I biogenesis
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
MyD88 cascade initiated on plasma membrane
Cristae formation
Drugs
Diseases
GWAS
Presence of antiphospholipid antibodies (
27098658
)
Facial emotion recognition (sad faces) (
28608620
)
Night sleep phenotypes (
27126917
)
Interacting Genes
53 interacting genes:
A2M
AIRIM
AP1M2
APOE
APP
BFSP2
BLMH
CDC37
CEP55
CTNNA3
CYP2C18
CYP2C8
CYP2C9
DNAJB1
DTX2
ELAVL3
EXOC6
EXOSC1
FARSA
FBXL12
FBXW4
GCDH
GEM
IFIT3
IFIT5
IMMT
LONP1
LOXL4
MAGEB2
MAST1
MKRN3
NFKB1
NXF1
OGT
PAXIP1
PI4K2A
PRDX2
PSEN1
RAB3A
RAD23A
RELA
RHEB
RNF32
SETDB1
SMAD1
SMAD4
SMURF1
STAMBPL1
STRN4
TARS3
TRAF6
TRIM59
TSSK3
65 interacting genes:
AKTIP
ALB
ANTKMT
ARMCX3
ASCC2
ATXN1
BAG6
BMI1
C10orf88
C8orf33
CALM1
CCT5
CDC37
CFAP263
CHD3
CSTF2
DISC1
DSCR9
ECSIT
EEF1A1
EP300
EXOSC10
FEZ1
FUBP1
HAP1
HIVEP1
HJURP
HMOX2
HNRNPD
HTRA2
KDM1A
KIF22
KPNA2
LRIF1
MARCHF5
MRPL44
NDEL1
NDUFB9
NEK2
NIPSNAP3A
NOS3
NRIP1
PDE4B
PFDN1
PIAS4
PLA2G15
PPOX
PRRC2A
RER1
RNF10
RNF26
SDHAF2
SMN1
SNAPIN
SRRT
STMN4
STX5
TAF1D
TK1
TNNT1
TRAF3IP1
TUBGCP3
TXNDC9
UBC
UBQLN4
Entrez ID
51295
10989
HPRD ID
12225
02658
Ensembl ID
ENSG00000130159
ENSG00000132305
Uniprot IDs
Q9BQ95
B4DS66
C9J406
Q16891
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Amyloid Fibril Formation
Regulation Of Protein Catabolic Process
Arachidonate Epoxygenase Activity
Lipoprotein Particle
Regulation Of MiRNA Metabolic Process
Epoxygenase P450 Pathway
NF-kappaB P50/p65 Complex
Positive Regulation Of Protein Metabolic Process
I-SMAD Binding
Cellular Response To Interleukin-6
Cytoplasm
Regulation Of Amyloid Fibril Formation
Response To Interleukin-6
Positive Regulation Of Proteolysis
Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Astrocyte Activation Involved In Immune Response
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen
Xenobiotic Catabolic Process
Caffeine Oxidase Activity
Magnesium Ion Binding
Response To Virus
Positive Regulation Of MiRNA Metabolic Process
Intermediate-density Lipoprotein Particle
Growth Factor Receptor Binding
Regulation Of MiRNA Transcription
Antiviral Innate Immune Response
Non-canonical NF-kappaB Signal Transduction
Regulation Of Protein Metabolic Process
SMAD Protein Complex
Neuronal Cell Body
Protein Ubiquitination
Oxidative Demethylation
Retinoic Acid 4-hydroxylase Activity
Heteromeric SMAD Protein Complex
Cellular Response To Nicotine
Protein Binding
Innate Immune Response
Cytosol
Arachidonate Metabolic Process
Omega-hydroxylase P450 Pathway
Defense Response To Virus
Defense Response To Tumor Cell
Demethylation
Protein Modification By Small Protein Conjugation
Positive Regulation Of Catabolic Process
Negative Regulation Of Long-term Synaptic Potentiation
Cellular Response To Amyloid-beta
Glutamatergic Synapse
Centrosome
Cytoplasm
Cytosol
Microtubule-based Process
Protein Binding
Protein-containing Complex
Nucleoplasm
Organelle Organization
Retrograde Axonal Transport
Axon Cytoplasm
Axonal Transport
Synaptic Vesicle
Nucleus
Organelle Localization
Cytoskeleton
Internal Peptidyl-lysine Acetylation
Mitochondrion
Microtubule
Gamma-tubulin Binding
Axo-dendritic Transport
Organelle Transport Along Microtubule
Negative Regulation Of Macroautophagy
Radial Glia-guided Pyramidal Neuron Migration
Protein Localization To Perinuclear Region Of Cytoplasm
Nuclear Body
Regulation Of Protein Metabolic Process
RNA Binding
Regulation Of Organelle Transport Along Microtubule
Transport Along Microtubule
Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Regulation Of DNA Metabolic Process
Internal Protein Amino Acid Acetylation
Regulation Of Telomere Maintenance Via Telomerase
Kinesin Complex
Vesicle Transport Along Microtubule
Regulation Of Metabolic Process
Negative Regulation Of Autophagy
Catabolic Process
Gamma-tubulin Complex
Regulation Of Telomere Maintenance
Centrosome Separation
Unfolded Protein Binding
Regulation Of Telomerase RNA Localization To Cajal Body
Cytoskeleton-dependent Intracellular Transport
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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