ECSIT and STAMBPL1

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		ECSIT	STAMBPL1
Gene Name		ECSIT signalling integrator	STAM binding protein-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Mitochondrion	Membrane
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Protein Binding Oxidoreductase Activity, Acting On NAD(P)H	Protein Binding Metallopeptidase Activity Metal Ion Binding
	Biological Process	Mesoderm Formation BMP Signaling Pathway Innate Immune Response Regulation Of Oxidoreductase Activity Oxidation-reduction Process	Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: A2M AP1M2 APOE APP BLMH CDC37 CEP55 CYP2C18 CYP2C8 CYP2C9 DNAJB1 ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 GCDH IFIT3 IFIT5 IMMT LONP1 LOXL4 MAST1 NFKB1 PAXIP1 PI4K2A PRDX2 PSEN1 RAB3A RAD23A RELA RHEB RNF32 SETDB1 SMAD1 SMAD4 SMURF1 STAMBPL1 STRN4 TRAF6 TRIM59	21 interactors: A2M CDC37 CEP72 ECSIT GNPTAB GOLGA2 IKZF3 INCA1 LAX1 MAGEA6 MAST1 PNMA1 PSEN1 RAB2A RNF11 RNF32 SMAD2 SMAD7 TCF4 TRIM27 TRIP13
Entrez ID		51295	57559
HPRD ID		12225	16486
Ensembl ID		ENSG00000130159	ENSG00000138134
Uniprot IDs		K7EMM0 Q9BQ95	Q96FJ0
PDB IDs			2ZNR 2ZNV
Enriched GO Terms of Interacting Partners?		Membrane Protein Proteolysis Regulation Of Interleukin-12 Biosynthetic Process Cellular Response To Interleukin-1 Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Epoxygenase P450 Pathway Membrane Protein Intracellular Domain Proteolysis Catabolic Process Response To Oxidative Stress Exogenous Drug Catabolic Process Drug Catabolic Process Response To Abiotic Stimulus Response To Interleukin-1 Protein Metabolic Process Response To Stress Exocytosis Negative Regulation Of Cell Death Proteolysis Response To Stimulus T Cell Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of MiRNA Metabolic Process Drug Metabolic Process Cellular Response To Growth Factor Stimulus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Response To Growth Factor Regulation Of Innate Immune Response Antigen Receptor-mediated Signaling Pathway Cellular Response To Nicotine Positive Regulation Of Interleukin-12 Biosynthetic Process Omega-hydroxylase P450 Pathway Cellular Response To Stimulus Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Apoptotic Process Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Programmed Cell Death Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of MiRNA Metabolic Process Negative Regulation Of Cholesterol Transport Regulation Of Interleukin-12 Production TRIF-dependent Toll-like Receptor Signaling Pathway Secretion By Cell Response To Drug SMAD Protein Complex Assembly Arachidonic Acid Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Cellular Localization Protein Localization Establishment Of Localization In Cell Secretion By Cell Protein Secretion Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Protein Transport Secretion Regulation Of Epithelial To Mesenchymal Transition Establishment Of Protein Localization Negative Regulation Of Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of BMP Signaling Pathway Regulation Of Binding Negative Regulation Of Protein Metabolic Process Cellular Protein Complex Localization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Complex Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Activin Receptor Signaling Pathway Regulation Of Protein Phosphorylation Post-embryonic Development Mesoderm Development Regulation Of Protein Metabolic Process Regulation Of Protein Binding Regulation Of Protein Kinase Activity Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Kinase Activity Regulation Of Catalytic Activity Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Immune System Process Intracellular Signal Transduction Regulation Of Phosphorylation Regulation Of Cell Morphogenesis Cellular Component Assembly Regulation Of Immune Response Cell Cycle Cellular Protein Localization Negative Regulation Of BMP Signaling Pathway Regulation Of Cellular Protein Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation
Tagcloud ?		1beta abolished adapter attributed augments consequence cytotrap evidenced evolutionarily gst hbx hbxdelta51 helenalin hepatitis ikappabalpha ikk interacted interacting kappab knockdown mechanistically nf p50 p65 pull tlr toll transactivates transfection
Tagcloud (Difference) ?		1beta abolished adapter attributed augments consequence cytotrap evidenced evolutionarily gst hbx hbxdelta51 helenalin hepatitis ikappabalpha ikk interacted interacting kappab knockdown mechanistically nf p50 p65 pull tlr toll transactivates transfection
Tagcloud (Intersection) ?