ECSIT and ELAVL3

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		ECSIT	ELAVL3
Gene Name		ECSIT signalling integrator	ELAV like neuron-specific RNA binding protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Mitochondrion
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Protein Binding Oxidoreductase Activity, Acting On NAD(P)H	Nucleotide Binding AU-rich Element Binding
	Biological Process	Mesoderm Formation BMP Signaling Pathway Innate Immune Response Regulation Of Oxidoreductase Activity Oxidation-reduction Process	Nervous System Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: A2M AP1M2 APOE APP BLMH CDC37 CEP55 CYP2C18 CYP2C8 CYP2C9 DNAJB1 ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 GCDH IFIT3 IFIT5 IMMT LONP1 LOXL4 MAST1 NFKB1 PAXIP1 PI4K2A PRDX2 PSEN1 RAB3A RAD23A RELA RHEB RNF32 SETDB1 SMAD1 SMAD4 SMURF1 STAMBPL1 STRN4 TRAF6 TRIM59	8 interactors: A2M CDC37 ECSIT ELAVL2 EWSR1 MAST1 NOS3 RNF32
Entrez ID		51295	1995
HPRD ID		12225	16024
Ensembl ID		ENSG00000130159	ENSG00000196361
Uniprot IDs		K7EMM0 Q9BQ95	Q14576
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Proteolysis Regulation Of Interleukin-12 Biosynthetic Process Cellular Response To Interleukin-1 Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Epoxygenase P450 Pathway Membrane Protein Intracellular Domain Proteolysis Catabolic Process Response To Oxidative Stress Exogenous Drug Catabolic Process Drug Catabolic Process Response To Abiotic Stimulus Response To Interleukin-1 Protein Metabolic Process Response To Stress Exocytosis Negative Regulation Of Cell Death Proteolysis Response To Stimulus T Cell Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of MiRNA Metabolic Process Drug Metabolic Process Cellular Response To Growth Factor Stimulus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Response To Growth Factor Regulation Of Innate Immune Response Antigen Receptor-mediated Signaling Pathway Cellular Response To Nicotine Positive Regulation Of Interleukin-12 Biosynthetic Process Omega-hydroxylase P450 Pathway Cellular Response To Stimulus Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Apoptotic Process Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Programmed Cell Death Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of MiRNA Metabolic Process Negative Regulation Of Cholesterol Transport Regulation Of Interleukin-12 Production TRIF-dependent Toll-like Receptor Signaling Pathway Secretion By Cell Response To Drug SMAD Protein Complex Assembly Arachidonic Acid Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway
Tagcloud ?		1beta abolished adapter attributed augments consequence cytotrap evidenced evolutionarily gst hbx hbxdelta51 helenalin hepatitis ikappabalpha ikk interacted interacting kappab knockdown mechanistically nf p50 p65 pull tlr toll transactivates transfection	24h abrogated acetylcysteine ameliorate ascl1b brdu ccne cdkn1b cdkn1c cns crx dpf eliminate embryogenesis ethanol exit fertilization hatching huc mitigate nac neural p57 pax6b photoreceptor reagent retinal sequestering unlikely
Tagcloud (Difference) ?		1beta abolished adapter attributed augments consequence cytotrap evidenced evolutionarily gst hbx hbxdelta51 helenalin hepatitis ikappabalpha ikk interacted interacting kappab knockdown mechanistically nf p50 p65 pull tlr toll transactivates transfection	24h abrogated acetylcysteine ameliorate ascl1b brdu ccne cdkn1b cdkn1c cns crx dpf eliminate embryogenesis ethanol exit fertilization hatching huc mitigate nac neural p57 pax6b photoreceptor reagent retinal sequestering unlikely
Tagcloud (Intersection) ?