IMMT and PPOX

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IMMT	PPOX
Gene Name		inner membrane protein, mitochondrial	protoporphyrinogen oxidase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Integral Component Of Membrane	Mitochondrial Intermembrane Space Intrinsic Component Of Mitochondrial Inner Membrane Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Poly(A) RNA Binding	Oxygen-dependent Protoporphyrinogen Oxidase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Biological_process Response To Cold Mitochondrial Calcium Ion Homeostasis	Porphyrin-containing Compound Metabolic Process Porphyrin-containing Compound Biosynthetic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Response To Drug Small Molecule Metabolic Process Oxidation-reduction Process
Pathways			Heme biosynthesis Metabolism of porphyrins
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AKTIP ALB ARMCX3 ASCC2 ATXN1 BAG6 BMI1 C10orf88 C8orf33 CALM1 CCDC113 CCT5 CDC37 CHD3 CSTF2 DISC1 ECSIT EEF1A1 EP300 EXOSC10 FAM173A FEZ1 FUBP1 HAP1 HIVEP1 HJURP HMOX2 HNRNPD KDM1A KIF22 KPNA2 LRIF1 MRPL44 NDEL1 NDUFB9 NEK2 NIPSNAP3A NOS3 PDE4DIP PFDN1 PIAS4 PLA2G15 PPOX PRRC2A RER1 SDHAF2 SMN1 SNAPIN SRRT STMN4 STX5 TAF1D TK1 TNNT1 TRAF3IP1 TUBGCP3 TXNDC9 UBQLN4	4 interactors: COPS5 HAP1 HNRNPD IMMT
Entrez ID		10989	5498
HPRD ID		02658	02953
Ensembl ID		ENSG00000132305	ENSG00000143224
Uniprot IDs		B9A067 Q16891	B3KT30 B4DY76 P50336
PDB IDs			3NKS 4IVM 4IVO
Enriched GO Terms of Interacting Partners?		Organelle Organization Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Localization Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Microtubule-based Process RNA Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Binding Regulation Of Metabolic Process Cellular Metabolic Process Posttranscriptional Regulation Of Gene Expression Establishment Of Localization In Cell Microtubule Polymerization Or Depolymerization Retrograde Axon Cargo Transport Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Cellular Macromolecule Biosynthetic Process Chromosome Segregation Embryo Development Cellular Process Macromolecule Biosynthetic Process Axon Cargo Transport Regulation Of Protein Metabolic Process Microtubule-based Transport RNA Processing Brain Development Cytoskeleton-dependent Intracellular Transport Centrosome Separation Embryo Development Ending In Birth Or Egg Hatching Organelle Localization Nervous System Development Chromosome Organization Regulation Of Protein Binding Head Development Anatomical Structure Development Regulation Of Cellular Process Microtubule Cytoskeleton Organization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Microtubule-based Movement Regulation Of Oxidoreductase Activity Regulation Of RNA Metabolic Process Establishment Of Organelle Localization	Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Exosomal Secretion Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Circadian Regulation Of Translation Exocytosis Cullin Deneddylation Hypothalamus Cell Differentiation Negative Regulation Of Beta-amyloid Formation Protein Deneddylation Retrograde Axon Cargo Transport Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Positive Regulation Of Synaptic Transmission, GABAergic Secretion By Cell Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration Mitochondrial Calcium Ion Homeostasis DNA Demethylation Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Telomere Maintenance Via Semi-conservative Replication Transcription, DNA-templated Regulation Of Beta-amyloid Formation Regulation Of Cilium Assembly RNA Biosynthetic Process Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Amyloid Precursor Protein Catabolic Process Telomere Maintenance Via Recombination Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Secretion Hypothalamus Development Positive Regulation Of Organelle Assembly Positive Regulation Of Cell Cycle G1/S Phase Transition Anterograde Axon Cargo Transport Positive Regulation Of Cellular Metabolic Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Cellular Homeostasis DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cation Channel Activity
Tagcloud ?			1082dupc ahp ahps aip biosynthetic cancerous catalyzing complication g111r germline hcc hccs heme hit hmbs hydroxymethylbilane intermittent l220x l416x oxidase pathomechanisms porphyria porphyrias protoporphyrinogen respective somatic suppressors variegate vp
Tagcloud (Difference) ?			1082dupc ahp ahps aip biosynthetic cancerous catalyzing complication g111r germline hcc hccs heme hit hmbs hydroxymethylbilane intermittent l220x l416x oxidase pathomechanisms porphyria porphyrias protoporphyrinogen respective somatic suppressors variegate vp
Tagcloud (Intersection) ?