IMMT and CCT5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IMMT	CCT5
Description		inner membrane mitochondrial protein	chaperonin containing TCP1 subunit 5
Image		No pdb structure
GO Annotations	Cellular Component	SAM Complex Mitochondrion Mitochondrial Envelope Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Mitochondrial Crista Junction MICOS Complex MIB Complex	Cytoplasm Centrosome Cytosol Chaperonin-containing T-complex Cytoskeleton Microtubule Cell Body Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	Nucleotide Binding MRNA 3'-UTR Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity G-protein Beta-subunit Binding Protein Folding Chaperone MRNA 5'-UTR Binding Beta-tubulin Binding Unfolded Protein Binding ATP-dependent Protein Folding Chaperone
	Biological Process	Inner Mitochondrial Membrane Organization Cristae Formation Mitochondrial Calcium Ion Homeostasis Neuron Cellular Homeostasis	Protein Folding Binding Of Sperm To Zona Pellucida Response To Virus Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Cristae formation	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS		Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)	Metabolite levels ( 23823483) Pain ( 22956598)
Interacting Genes		65 interacting genes: AKTIP ALB ANTKMT ARMCX3 ASCC2 ATXN1 BAG6 BMI1 C10orf88 C8orf33 CALM1 CCT5 CDC37 CFAP263 CHD3 CSTF2 DISC1 DSCR9 ECSIT EEF1A1 EP300 EXOSC10 FEZ1 FUBP1 HAP1 HIVEP1 HJURP HMOX2 HNRNPD HTRA2 KDM1A KIF22 KPNA2 LRIF1 MARCHF5 MRPL44 NDEL1 NDUFB9 NEK2 NIPSNAP3A NOS3 NRIP1 PDE4B PFDN1 PIAS4 PLA2G15 PPOX PRRC2A RER1 RNF10 RNF26 SDHAF2 SMN1 SNAPIN SRRT STMN4 STX5 TAF1D TK1 TNNT1 TRAF3IP1 TUBGCP3 TXNDC9 UBC UBQLN4	23 interacting genes: ACTA1 ACTA2 ACTB CEBPA DCAF12 DUXAP9 ELP1 ERCC6 HDAC3 IMMT MCPH1 OGT PDCL SPMAP2 SUMO2 SUMO4 TBC1D17 TCP1 TERT TP53 VHL XRN1 ZNRD2
Entrez ID		10989	22948
HPRD ID		02658	06468
Ensembl ID		ENSG00000132305	ENSG00000150753
Uniprot IDs		B4DS66 C9J406 Q16891	B4DDU6 B4DX08 B4DYC8 B7ZAR1 E7ENZ3 E9PCA1 P48643 V9HW37
PDB IDs			5UYX 5UYZ 6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8 7LUM 7LUP 7NVL 7NVM 7NVN 7NVO 7TRG 7TTN 7TTT 7TUB 7WU7 7WZ3 7X0A 7X0S 7X0V 7X3J 7X3U 7X6Q 7X7Y 8AJM 8AJO 8HKI 8I1U 8I9U 8IB8 8SFE 8SFF 8SG8 8SG9 8SGC 8SGL 8SGQ 8SH9 8SHA 8SHD 8SHE 8SHF 8SHG 8SHL 8SHN 8SHO 8SHP 8SHQ 8SHT
Enriched GO Terms of Interacting Partners?		Centrosome Cytoplasm Cytosol Microtubule-based Process Protein Binding Protein-containing Complex Nucleoplasm Organelle Organization Retrograde Axonal Transport Axon Cytoplasm Axonal Transport Synaptic Vesicle Nucleus Organelle Localization Cytoskeleton Internal Peptidyl-lysine Acetylation Mitochondrion Microtubule Gamma-tubulin Binding Axo-dendritic Transport Organelle Transport Along Microtubule Negative Regulation Of Macroautophagy Radial Glia-guided Pyramidal Neuron Migration Protein Localization To Perinuclear Region Of Cytoplasm Nuclear Body Regulation Of Protein Metabolic Process RNA Binding Regulation Of Organelle Transport Along Microtubule Transport Along Microtubule Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA Metabolic Process Internal Protein Amino Acid Acetylation Regulation Of Telomere Maintenance Via Telomerase Kinesin Complex Vesicle Transport Along Microtubule Regulation Of Metabolic Process Negative Regulation Of Autophagy Catabolic Process Gamma-tubulin Complex Regulation Of Telomere Maintenance Centrosome Separation Unfolded Protein Binding Regulation Of Telomerase RNA Localization To Cajal Body Cytoskeleton-dependent Intracellular Transport	Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Mesenchyme Migration Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Chromosome Organization Positive Regulation Of RNA Metabolic Process Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Protein Localization To Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Protein Stability Regulation Of Metabolic Process Cell Body Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of DNA-templated Transcription Initiation Protein Tag Activity Replicative Senescence Regulation Of Stem Cell Proliferation Regulation Of DNA Biosynthetic Process Chromatin DNA Binding Regulation Of Primary Metabolic Process Positive Regulation Of Protein Localization To Nucleus Regulation Of Cell Cycle Mitochondrion Organization Negative Regulation Of Telomere Maintenance Via Telomerase PML Body Regulation Of Telomere Maintenance Telomerase RNA Binding Regulation Of DNA Metabolic Process Regulation Of Protein Metabolic Process Ubiquitin-like Protein Ligase Binding Regulation Of RNA Metabolic Process Negative Regulation Of Stem Cell Proliferation Response To X-ray Nuclear Matrix Histone Deacetylase Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Circadian Rhythm Negative Regulation Of DNA Metabolic Process Cellular Response To Hypoxia Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
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