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COPS4 and COPS3
Number of citations of the paper that reports this interaction (PubMedID
11285227
)
43
Data Source:
HPRD
(in vivo, in vitro)
COPS4
COPS3
Description
COP9 signalosome subunit 4
COP9 signalosome subunit 3
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Synaptic Vesicle
COP9 Signalosome
Nuclear Speck
Cell Junction
Cytoplasmic Vesicle
Protein-containing Complex
Synapse
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
COP9 Signalosome
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
DeNEDDylase Activity
Protein Binding
Biological Process
Protein Deneddylation
Protein Neddylation
Regulation Of Protein Neddylation
Protein Deneddylation
In Utero Embryonic Development
Ubiquitin-dependent Protein Catabolic Process
Signal Transduction
Response To Light Stimulus
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Protein Neddylation
Regulation Of Protein Neddylation
Pathways
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation
RHOBTB1 GTPase cycle
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Alanine aminotransferase levels (
33547301
)
Mean corpuscular volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Neutrophil percentage of white cells (
32888494
)
Reticulocyte count (
32888494
)
Interacting Genes
28 interacting genes:
BRME1
CCDC85B
CEBPA
COPS2
COPS3
COPS5
COPS6
COPS7A
COPS8
CUL5
DSCR9
FOS
GPS1
HUNK
IKBKB
IL1RN
KRT19
LCOR
MBIP
PCDHB12
PEX14
RAB18
RBX1
RCBTB2
TP53
UBQLN1
USHBP1
YWHAQ
32 interacting genes:
ARAF
ARF4
C17orf75
CEBPA
CEBPE
COPS2
COPS4
COPS5
COPS6
COPS7A
COPS8
CSNK2A1
CSNK2B
CUL5
FLAD1
FRS3
GPS1
IKBKB
IKBKG
IL1RN
IRF5
ITGB2
KRT80
LRP2BP
MCPH1
MLF1
NABP1
PRXL2B
RAF1
SOS1
TP53
UBC
Entrez ID
51138
8533
HPRD ID
09888
07262
Ensembl ID
ENSG00000138663
ENSG00000141030
Uniprot IDs
A0A0S2Z5H7
B3KM48
D6RAX7
Q9BT78
B4DN01
Q9UNS2
PDB IDs
4D0P
4D10
4D18
4WSN
6R6H
6R7F
6R7H
6R7I
6R7N
8H38
8H3A
8H3F
4D10
4D18
4WSN
6R6H
6R7F
6R7H
6R7I
6R7N
8H38
8H3A
8H3F
Enriched GO Terms of Interacting Partners
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Protein Deneddylation
Protein Neddylation
Regulation Of Protein Neddylation
COP9 Signalosome
Regulation Of Post-translational Protein Modification
Protein Modification By Small Protein Removal
Protein Modification By Small Protein Conjugation
Post-translational Protein Modification
Regulation Of Protein Modification Process
Regulation Of Protein Metabolic Process
COP9 Signalosome Assembly
Protein Modification Process
Intracellular Signaling Cassette
Cytosol
Regulation Of Primary Metabolic Process
Negative Regulation Of Mitophagy
Metal-dependent Deubiquitinase Activity
Protein-containing Complex
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Cul5-RING Ubiquitin Ligase Complex
Cullin-RING Ubiquitin Ligase Complex
Intracellular Signal Transduction
Regulation Of Macromolecule Metabolic Process
Nucleoplasm
Cytokine-mediated Signaling Pathway
Cellular Response To Tumor Necrosis Factor
DNA-templated Transcription
Cellular Response To Stress
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Stem Cell Proliferation
Nucleus
Response To Tumor Necrosis Factor
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of RNA Metabolic Process
Histone Deacetylase Binding
Nuclear Matrix
Macromolecule Metabolic Process
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Metabolic Process
Response To Glucocorticoid
Cellular Response To Hypoxia
Medium-term Memory
Cellular Response To Prolactin
Protein Metabolic Process
Interleukin-1 Type I Receptor Antagonist Activity
Interleukin-1 Type II Receptor Antagonist Activity
Peroxisome Transport Along Microtubule
Protein Deneddylation
Regulation Of Protein Neddylation
Protein Neddylation
COP9 Signalosome
Protein Modification By Small Protein Removal
Regulation Of Protein Metabolic Process
Cytosol
Regulation Of Protein Modification Process
Regulation Of Post-translational Protein Modification
Protein Modification By Small Protein Conjugation
Cytokine-mediated Signaling Pathway
Post-translational Protein Modification
Protein Modification Process
Regulation Of Primary Metabolic Process
Cytoplasm
Intracellular Signal Transduction
Protein Kinase CK2 Complex
Symbiont-mediated Disruption Of Host Cell PML Body
ERBB Signaling Pathway
Regulation Of Macromolecule Metabolic Process
Intracellular Signaling Cassette
Regulation Of Ubiquitin-dependent Protein Catabolic Process
COP9 Signalosome Assembly
Cell Surface Receptor Signaling Pathway
Signal Transduction
Identical Protein Binding
Nucleoplasm
DeNEDDylase Activity
Regulation Of Proteolysis
IkappaB Kinase Complex
Regulation Of Metabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Transferrin Receptor Binding
Macromolecule Metabolic Process
Metal-dependent Deubiquitinase Activity
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Type II Interferon-mediated Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Protein Metabolic Process
Protein Heterodimerization Activity
Inflammatory Response
Protein Phosphorylation
Protein Binding
Immune Response-activating Signaling Pathway
Regulation Of Proteasomal Protein Catabolic Process
Schwann Cell Development
Regulation Of Intracellular Signal Transduction
Phosphorylation
Protein Serine/threonine Kinase Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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