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COPS4 and COPS8
Number of citations of the paper that reports this interaction (PMID
11337588
)
171
Data Source:
BioGRID
(pull down, biochemical)
HPRD
(in vitro, in vivo)
COPS4
COPS8
Gene Name
COP9 signalosome subunit 4
COP9 signalosome subunit 8
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Synaptic Vesicle
COP9 Signalosome
Cell Junction
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Cytoplasm
COP9 Signalosome
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Biological Process
Protein Deneddylation
Cullin Deneddylation
Activation Of NF-kappaB-inducing Kinase Activity
Negative Regulation Of Cell Proliferation
Cullin Deneddylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
17 interactors:
C19orf57
CCDC85B
COPS2
COPS3
COPS5
COPS6
COPS7A
COPS8
CUL5
FOS
IKBKB
JUN
MBIP
RCBTB2
TP53
USHBP1
YWHAQ
17 interactors:
COPS2
COPS3
COPS4
COPS5
COPS6
COPS7A
CUL1
CUL5
DDB1
EIF3E
GPS1
ITPK1
JUN
MAPRE1
NFKBIA
TP53
USHBP1
Entrez ID
51138
10920
HPRD ID
09888
16737
Ensembl ID
ENSG00000138663
Uniprot IDs
B3KM48
Q9BT78
Q99627
PDB IDs
Enriched GO Terms of Interacting Partners
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Cullin Deneddylation
Protein Deneddylation
Protein Modification By Small Protein Removal
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor Signaling Pathway
Apoptotic Signaling Pathway
Cellular Protein Modification Process
Regulation Of Intracellular Signal Transduction
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Intracellular Signal Transduction
Transforming Growth Factor Beta Receptor Signaling Pathway
Activation Of Innate Immune Response
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Release Of Cytochrome C From Mitochondria
Regulation Of Signal Transduction
Response To Radiation
Transcription From RNA Polymerase II Promoter
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Innate Immune Response
Intrinsic Apoptotic Signaling Pathway
Response To Transforming Growth Factor Beta
Cellular Response To Extracellular Stimulus
Regulation Of Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Fc-epsilon Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Cellular Response To Calcium Ion
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Myeloid Leukocyte Differentiation
Response To Abiotic Stimulus
Negative Regulation Of Transcription, DNA-templated
Regulation Of Innate Immune Response
Response To Growth Factor
Negative Regulation Of Nucleic Acid-templated Transcription
SMAD Protein Signal Transduction
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Mitochondrion Organization
Cullin Deneddylation
Protein Deneddylation
Protein Modification By Small Protein Removal
Viral Process
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Regulation Of Cell Cycle
Response To Abiotic Stimulus
Protein Import Into Nucleus
Apoptotic Signaling Pathway
Nuclear Import
Cell Proliferation
Cell Cycle Arrest
Protein Metabolic Process
Protein Import
Protein Import Into Nucleus, Translocation
Release Of Cytochrome C From Mitochondria
Cellular Macromolecule Catabolic Process
Protein Localization To Nucleus
Response To Radiation
Circadian Rhythm
Interaction With Symbiont
Intrinsic Apoptotic Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Protein Localization To Organelle
Modification-dependent Protein Catabolic Process
Apoptotic Process
Protein Monoubiquitination
Programmed Cell Death
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cell Death
Negative Regulation Of DNA Binding
Death
Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Protein Catabolic Process
Toll-like Receptor 10 Signaling Pathway
Regulation Of Binding
Mitotic Cell Cycle Phase Transition
Nucleocytoplasmic Transport
Cell Cycle Phase Transition
Nuclear Transport
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Cellular Response To UV
Cellular Response To Potassium Ion Starvation
Positive Regulation Of Neuron Apoptotic Process
Toll-like Receptor 2 Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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