SUV420H1 and SMARCD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SUV420H1	SMARCD1
Gene Name		suppressor of variegation 4-20 homolog 1 (Drosophila)	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Nuclear Chromosome, Centromeric Region	SWI/SNF Complex NpBAF Complex NBAF Complex
	Molecular Function	Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H4-K20 Specific)	Transcription Coactivator Activity Protein Binding Protein Complex Scaffold
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Muscle Organ Development Histone H4-K20 Trimethylation	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Chromatin-mediated Maintenance Of Transcription
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691)
Protein-Protein Interactions		3 interactors: ESR1 HIST1H4A SMARCD1	44 interactors: ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CORO1A DPF3 EGFL7 ESR1 FEZ1 FOS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KRT15 KRT18 LDOC1 MED4 NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 SUV420H1 TNIP2 TP53 USHBP1 VPS37B YWHAG
Entrez ID		51111	6602
HPRD ID		11616	03438
Ensembl ID		ENSG00000110066	ENSG00000066117
Uniprot IDs		B5MCB3 Q4FZB7	Q96GM5
PDB IDs		3S8P
Enriched GO Terms of Interacting Partners?		Chromatin Remodeling Chromatin Modification Chromatin Organization Chromosome Organization Nucleosome Organization Chromatin Assembly Or Disassembly Regulation Of Gene Expression, Epigenetic Histone H4-K20 Demethylation Prostate Epithelial Cord Elongation Negative Regulation Of Megakaryocyte Differentiation Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Negative Regulation Of Hematopoietic Progenitor Cell Differentiation DNA Replication-dependent Nucleosome Assembly Chromatin-mediated Maintenance Of Transcription Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis DNA Methylation On Cytosine Vagina Development Nucleosome Disassembly Uterus Development Chromatin Silencing At RDNA Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Megakaryocyte Differentiation Cellular Response To Estradiol Stimulus Prostate Gland Growth Organelle Organization Branching Involved In Prostate Gland Morphogenesis Mammary Gland Epithelial Cell Proliferation Female Genitalia Development Positive Regulation Of Monooxygenase Activity Branch Elongation Of An Epithelium CENP-A Containing Nucleosome Assembly Cellular Response To Estrogen Stimulus Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Exchange Chromatin Silencing DNA Replication-independent Nucleosome Assembly Axis Elongation Histone Lysine Demethylation Histone Demethylation Protein Demethylation Androgen Metabolic Process Prostate Gland Epithelium Morphogenesis Regulation Of Nitric-oxide Synthase Activity	RNA Biosynthetic Process Gene Expression Transcription, DNA-templated RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Chromatin Organization Regulation Of Gene Expression Cellular Response To Organic Substance Response To Organic Substance Developmental Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of RNA Metabolic Process Anatomical Structure Development Transcription From RNA Polymerase II Promoter System Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Cell Death Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Multicellular Organismal Development DNA-templated Transcription, Initiation Hormone-mediated Signaling Pathway Regulation Of Cell Proliferation Cellular Response To Hormone Stimulus Regulation Of Cellular Process Chromatin Modification
Tagcloud ?		aspects breast cancerous clearly clinicopathological ectopic elucidate global goal h3k9me3 h4 h4k20 h4k20me3 importantly independently invasion invasiveness knockdown luminal lysine mammary methyltransferases modification mostly multivariate pathological trimethylation univariate
Tagcloud (Difference) ?		aspects breast cancerous clearly clinicopathological ectopic elucidate global goal h3k9me3 h4 h4k20 h4k20me3 importantly independently invasion invasiveness knockdown luminal lysine mammary methyltransferases modification mostly multivariate pathological trimethylation univariate
Tagcloud (Intersection) ?