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PARD6A and TCP10
Number of citations of the paper that reports this interaction (PMID
10934474
)
205
Data Source:
HPRD
(two hybrid)
PARD6A
TCP10
Gene Name
par-6 family cell polarity regulator alpha
t-complex 10
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Nucleus
Cytosol
Plasma Membrane
Tight Junction
Cell Cortex
Protein Complex
Apical Part Of Cell
Cytosol
Molecular Function
Protein Kinase C Binding
Protein Binding
Transcription Factor Binding
Rho GTPase Binding
GTP-dependent Protein Binding
Biological Process
Cell Cycle
Transforming Growth Factor Beta Receptor Signaling Pathway
Viral Process
Cell Junction Assembly
Cell-cell Junction Organization
Cell-cell Junction Maintenance
Cell Division
Tight Junction Assembly
Pathways
Loss of Function of TGFBR2 in Cancer
Cell junction organization
TGFBR2 MSI Frameshift Mutants in Cancer
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Tight junction interactions
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
SMAD2/3 MH2 Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
TGFBR1 KD Mutants in Cancer
Signaling by Wnt
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
beta-catenin independent WNT signaling
Cell-cell junction organization
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
Asymmetric localization of PCP proteins
PCP/CE pathway
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
24 interactors:
CDC42
CDH5
CRB3
DVL2
ECT2
GLS
MAP2K5
MARK2
MARK4
PARD3
PARD6B
PLCB1
PLCB3
PRKCG
PRKCH
PRKCI
PRKCZ
RAC1
RHOQ
TCP10
TGFBR1
WDR83
YWHAH
YWHAZ
4 interactors:
APP
PARD6A
PARD6B
UBC
Entrez ID
50855
6953
HPRD ID
06316
01752
Ensembl ID
ENSG00000102981
Uniprot IDs
Q9NPB6
D1MPS5
Q12799
PDB IDs
1WMH
Enriched GO Terms of Interacting Partners
?
Intracellular Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Cell-cell Junction Organization
Nervous System Development
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Signaling
Cell Communication
Tight Junction Assembly
Signal Transduction
Regulation Of Cell Death
Regulation Of Cellular Component Organization
System Development
Positive Regulation Of Signal Transduction
Apical Junction Assembly
Positive Regulation Of Kinase Activity
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Transport
Establishment Or Maintenance Of Cell Polarity
Regulation Of Cellular Localization
Regulation Of Apoptotic Process
Positive Regulation Of Transferase Activity
Cell Junction Assembly
Multicellular Organismal Development
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Phosphorylation
Positive Regulation Of Programmed Cell Death
Response To Growth Factor
Generation Of Neurons
Wound Healing
Anatomical Structure Development
Cellular Response To Stimulus
Positive Regulation Of Cell Death
Cell-cell Junction Assembly
Neurogenesis
Regulation Of Establishment Of Protein Localization
Regulation Of Phosphorylation
Response To Wounding
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cell Projection Organization
Regulation Of Cell Projection Organization
Regulation Of Protein Phosphorylation
Developmental Process
Regulation Of Protein Localization
Regulation Of Kinase Activity
Cellular Component Assembly
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Catalytic Activity
Positive Regulation Of Cell Differentiation
Regulation Of Cell Differentiation
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Tight Junction Assembly
Apical Junction Assembly
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Cell-cell Junction Assembly
Notch Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Synaptic Growth At Neuromuscular Junction
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Intracellular Receptor Signaling Pathway
Cell Junction Assembly
Cell-cell Junction Organization
Collateral Sprouting In Absence Of Injury
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle Phase Transition
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cell Cycle
Collateral Sprouting
Axon Midline Choice Point Recognition
Positive Regulation Of Cell Cycle
Positive Regulation Of Proteolysis
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Neuron Remodeling
Cell-cell Junction Maintenance
Regulation Of Mitotic Cell Cycle
Viral Protein Processing
Cell Division
Cellular Component Assembly
Regulation Of Cell Cycle Process
Axonogenesis
Cellular Copper Ion Homeostasis
Viral Process
Axon Development
Cellular Response To Growth Factor Stimulus
Cell Morphogenesis Involved In Neuron Differentiation
Response To Growth Factor
Notch Receptor Processing
Copper Ion Homeostasis
Suckling Behavior
Virion Assembly
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Neuron Projection Morphogenesis
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Cellular Component Maintenance
Regulation Of Proteolysis
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Tagcloud (Intersection)
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