TCP10 and PARD6B

Number of citations of the paper that reports this interaction (PMID 10934474)
205

Data Source:
HPRD (two hybrid)

		TCP10	PARD6B
Gene Name		t-complex 10	par-6 family cell polarity regulator beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Cytosol Plasma Membrane Tight Junction Cell Cortex Protein Complex Apical Part Of Cell Extracellular Vesicular Exosome
	Molecular Function		Protein Binding
	Biological Process		Protein Complex Assembly Cell-cell Junction Assembly Cell Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Junction Assembly Cell-cell Junction Organization Cell Division Tight Junction Assembly
Pathways			Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS			Bipolar disorder ( 21771265)
Protein-Protein Interactions		4 interactors: APP PARD6A PARD6B UBC	22 interactors: APP CDC42 CEP76 GMCL1 GOLGA2 HTRA1 MPP5 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RHOJ RHOQ TCP10 WDR83 YWHAB YWHAH YWHAZ
Entrez ID		6953	84612
HPRD ID		01752	18703
Ensembl ID			ENSG00000124171
Uniprot IDs		D1MPS5 Q12799	Q9BYG5
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Tight Junction Assembly Apical Junction Assembly Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cell-cell Junction Assembly Notch Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Intracellular Receptor Signaling Pathway Cell Junction Assembly Cell-cell Junction Organization Collateral Sprouting In Absence Of Injury Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cell-cell Junction Maintenance Regulation Of Mitotic Cell Cycle Viral Protein Processing Cell Division Cellular Component Assembly Regulation Of Cell Cycle Process Axonogenesis Cellular Copper Ion Homeostasis Viral Process Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Growth Factor Notch Receptor Processing Copper Ion Homeostasis Suckling Behavior Virion Assembly Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Neuron Projection Morphogenesis Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Component Maintenance Regulation Of Proteolysis	Cell-cell Junction Organization Enzyme Linked Receptor Protein Signaling Pathway Tight Junction Assembly Regulation Of Cellular Component Organization Membrane Organization Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Apical Junction Assembly Wound Healing Response To Growth Factor Platelet Activation Positive Regulation Of Cell Death Actin Filament-based Process Cellular Protein Localization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Intracellular Signal Transduction Blood Coagulation Regulation Of Cellular Localization Hemostasis Response To Wounding Cellular Component Assembly Regulation Of Apoptotic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Protein Localization Cell-cell Junction Assembly Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Glucose Import Neurogenesis Positive Regulation Of Glucose Transport Regulation Of Body Fluid Levels Nervous System Development Regulation Of Organelle Organization Actin Cytoskeleton Organization Defense Response Establishment Of Golgi Localization Neuron Development Protein Localization To Membrane Cellular Localization Neuron Projection Morphogenesis Anatomical Structure Morphogenesis Establishment Or Maintenance Of Cell Polarity Protein Localization Regulation Of Glucose Import Positive Regulation Of Mitochondrion Organization
Tagcloud ?			adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify vps4b wizened
Tagcloud (Difference) ?			adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify vps4b wizened
Tagcloud (Intersection) ?