SERPINE1 and ACTN4

  • Number of citations of the paper that reports this interaction (PMID 15493875)
  • 2
  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

SERPINE1

ACTN4

Gene Name serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 actinin, alpha 4
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
Protein-Protein Interactions 19 interactors: ACTN4 ELANE F2 IGFBP5 KLK2 KRT18 LRP1 LRP1B LRP2 MMP3 ORM1 PLAT PLAU PLG SGTA SGTB UBQLN1 UBQLN4 VTN 43 interactors: ACTC1 ACTN3 ADORA2A ATP6V1B1 ATXN7 BMP7 CAMK2A CAMK2B CAMK2G CDKN2A COIL COL17A1 ESR1 GSN HDAC7 INO80 ITGB1 KPNA2 LRRC7 MAGI1 MAPK7 MEF2A MYOZ1 MYOZ2 NEB NOS2 NOS3 PDLIM1 POT1 PTPN11 PTPN6 RPS27 SACS SERPINE1 SLC2A4 SLC9A3R2 STAT1 TJP1 TRIM3 TXN UCHL5 USP6NL VDR
Entrez ID 5054 81
HPRD ID 01418 05222
Ensembl ID ENSG00000106366
Uniprot IDs P05121 O43707
PDB IDs 1A7C 1B3K 1C5G 1DB2 1DVM 1DVN 1LJ5 1OC0 3CVM 3EOX 3PB1 3Q02 3Q03 3R4L 3UT3 4AQH 9PAI 1WLX 1YDI 2R0O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bag1  bcl2l2  bctis  ccna2  comprehend  ctsb  deregulations  fgf1  fosl1  gabrp  gsn  hnepi  id2  il6r  itgb4  klf5  klk5  map2k7  microdissected  ngfb  ngfr  ontological  pappa  plau  scgb1d2  scgb2a1  thbs1  thbs2 
1beta  actin  actinin  blocks  coactivator  cytosol  defective  fails  filtration  focal  fsgs  glomerular  glomerulosclerosis  ikappabalpha  k255e  mechanistically  nphs1  p50  p65  podocytes  potentiate  proteinuria  recruit  reporter  segmental  specialized  terminally  tnfalpha  translocate 
Tagcloud (Difference) ?
bag1  bcl2l2  bctis  ccna2  comprehend  ctsb  deregulations  fgf1  fosl1  gabrp  gsn  hnepi  id2  il6r  itgb4  klf5  klk5  map2k7  microdissected  ngfb  ngfr  ontological  pappa  plau  scgb1d2  scgb2a1  thbs1  thbs2 
1beta  actin  actinin  blocks  coactivator  cytosol  defective  fails  filtration  focal  fsgs  glomerular  glomerulosclerosis  ikappabalpha  k255e  mechanistically  nphs1  p50  p65  podocytes  potentiate  proteinuria  recruit  reporter  segmental  specialized  terminally  tnfalpha  translocate 
Tagcloud (Intersection) ?