PRDX1 and SH2D1B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PRDX1	SH2D1B
Gene Name		peroxiredoxin 1	SH2 domain containing 1B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Euchromatin Nucleolus Cytoplasm Mitochondrial Matrix Peroxisomal Matrix Cytosol Melanosome Extracellular Vesicular Exosome	Intracellular
	Molecular Function	Peroxidase Activity Protein Binding Thioredoxin Peroxidase Activity Heme Binding Protein Homodimerization Activity Poly(A) RNA Binding	Protein Binding Protein Binding, Bridging
	Biological Process	Response To Reactive Oxygen Species Skeletal System Development Retina Homeostasis Cell Proliferation Removal Of Superoxide Radicals Regulation Of Stress-activated MAPK Cascade Erythrocyte Homeostasis Natural Killer Cell Mediated Cytotoxicity Regulation Of NF-kappaB Import Into Nucleus Hydrogen Peroxide Catabolic Process Oxidation-reduction Process	Leukocyte Activation Involved In Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Innate Immune Response
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ABL1 ADH5 BTRC CALM1 CLEC4G EGFR GAPDH IRF3 LUC7L MTRNR2L1 MYC MYD88 PPP2R1A PPP2R1B PRDX4 SESN1 SESN2 SH2D1B SMARCD1 SNCA TERF1 UBE3A VHL YWHAQ	8 interactors: APP CD244 CD84 ERBB2 LY9 PRDX1 SLAMF1 TRIM54
Entrez ID		5052	117157
HPRD ID		01458	12248
Ensembl ID		ENSG00000117450	ENSG00000198574
Uniprot IDs		Q06830	O14796
PDB IDs		2RII 3HY2
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Regulation Of Apoptotic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Response To Organic Substance Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Regulation Of Oxidoreductase Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Protein Metabolic Process Positive Regulation Of Programmed Cell Death Response To Stimulus Positive Regulation Of Cell Death Regulation Of Phospholipase Activity Apoptotic Process Programmed Cell Death Intracellular Signal Transduction Cellular Response To Organic Substance Cell Death Death Regulation Of Response To Reactive Oxygen Species Regulation Of Cellular Ketone Metabolic Process Peptidyl-cysteine S-nitrosylation Innate Immune Response Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Oxidoreductase Activity Response To Lipid Regulation Of Protein Stability Response To Lipopolysaccharide Developmental Process Positive Regulation Of Signal Transduction Response To Molecule Of Bacterial Origin Cellular Response To Growth Factor Stimulus Type I Interferon Biosynthetic Process Immune Response Regulation Of Immune System Process Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Response To Growth Factor Regulation Of Cell Cycle Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Organic Cyclic Compound Regulation Of Cellular Amino Acid Metabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Phosphorylation Cell Cycle Process Response To Fibroblast Growth Factor	Immune System Process Wound Healing Response To Wounding Neuromuscular Junction Development Blood Coagulation Hemostasis Locomotion Defense Response Synaptic Growth At Neuromuscular Junction Regulation Of Body Fluid Levels Movement Of Cell Or Subcellular Component Collateral Sprouting In Absence Of Injury Negative Regulation Of Immature T Cell Proliferation In Thymus Synapse Organization Regulation Of Microtubule-based Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Innate Immune Response Axon Choice Point Recognition Response To Stress Leukocyte Migration Negative Regulation Of T Cell Differentiation In Thymus Neuron Remodeling Response To Stimulus Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Translation Positive Regulation Of Transcription From RNA Polymerase I Promoter
Tagcloud ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Difference) ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Intersection) ?