SH2D1B and LY9

Number of citations of the paper that reports this interaction (PMID 11689425)
15

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SH2D1B	LY9
Gene Name		SH2 domain containing 1B	lymphocyte antigen 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Binding, Bridging	Molecular_function Receptor Activity
	Biological Process	Leukocyte Activation Involved In Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Innate Immune Response	Cell Adhesion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP CD244 CD84 ERBB2 LY9 PRDX1 SLAMF1 TRIM54	3 interactors: AP2M1 SH2D1A SH2D1B
Entrez ID		117157	4063
HPRD ID		12248	02817
Ensembl ID		ENSG00000198574	ENSG00000122224
Uniprot IDs		O14796	Q05CA2 Q0VAI0 Q9HBG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune System Process Wound Healing Response To Wounding Neuromuscular Junction Development Blood Coagulation Hemostasis Locomotion Defense Response Synaptic Growth At Neuromuscular Junction Regulation Of Body Fluid Levels Movement Of Cell Or Subcellular Component Collateral Sprouting In Absence Of Injury Negative Regulation Of Immature T Cell Proliferation In Thymus Synapse Organization Regulation Of Microtubule-based Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Innate Immune Response Axon Choice Point Recognition Response To Stress Leukocyte Migration Negative Regulation Of T Cell Differentiation In Thymus Neuron Remodeling Response To Stimulus Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Translation Positive Regulation Of Transcription From RNA Polymerase I Promoter	Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Immune System Process Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Immune System Process Positive Regulation Of Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Regulation Of Immune Response Positive Regulation Of Immune System Process Cell-cell Signaling Clathrin-mediated Endocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Protein Localization To Plasma Membrane Cellular Defense Response Immune Response Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Ephrin Receptor Signaling Pathway Positive Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity
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