NME1 and WDYHV1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NME1	WDYHV1
Gene Name		NME/NM23 nucleoside diphosphate kinase 1	WDYHV motif containing 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Ruffle Membrane Extracellular Vesicular Exosome	Nucleus Cytosol
	Molecular Function	Magnesium Ion Binding Deoxyribonuclease Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Ribosomal Small Subunit Binding Poly(A) RNA Binding	Protein Binding Protein-N-terminal Glutamine Amidohydrolase Activity
	Biological Process	Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Catabolic Process Endocytosis Nervous System Development Negative Regulation Of Cell Proliferation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Cell Differentiation Regulation Of Apoptotic Process Positive Regulation Of DNA Binding Small Molecule Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Nucleobase-containing Small Molecule Metabolic Process	Cellular Protein Modification Process
Pathways		Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APEX1 AURKA CCND3 FXR2 GORASP2 ITGB1 KSR1 MIF NIF3L1 NME2 NME3 NME4 PID1 POLR1C PRUNE RAC1 RORA RORB RRAD SET SMARCD1 SOX30 SREK1IP1 TERF1 TIAM1 TNPO2 WDYHV1	88 interactors: ACTB ACTG1 AMOT AMOTL2 APIP ASL BIRC2 BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CCDC102B CCDC184 CDA CDR2 COIL CRYAA CTH DAB1 DCTPP1 DHPS EDARADD EIF2B1 ETV6 FTH1 GAS7 GMDS GNMT GOLGA2 HPRT1 HSD17B14 JUP KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCH10 MDFI MIF MTUS2 NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PTS PYGM RABAC1 RAD54L RBBP8 RBPMS RPIA SEPT3 SFN SIAH1 SMN1 STX11 THAP1 TMEM239 TNR TOLLIP TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341
Entrez ID		4830	55093
HPRD ID		01131	07653
Ensembl ID		ENSG00000239672	ENSG00000156795
Uniprot IDs		P15531	Q96HA8
PDB IDs		1JXV 1UCN 2HVD 2HVE 3L7U 4ENO	3C9Q
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process Regulation Of Cell Death CTP Biosynthetic Process Positive Regulation Of Metabolic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Regulation Of Metabolic Process Response To Organic Cyclic Compound Pyrimidine Nucleoside Metabolic Process Regulation Of Cell Cycle Response To Hormone Pyrimidine Nucleotide Metabolic Process Cellular Response To Lipid Nucleoside Triphosphate Biosynthetic Process Nucleosome Disassembly Mitotic Cell Cycle Nucleobase-containing Small Molecule Interconversion Regulation Of Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Development Response To Drug Positive Regulation Of Cell Projection Organization Response To Organic Substance Positive Regulation Of Cell Cycle Response To Lipid Ribonucleotide Metabolic Process Positive Regulation Of Mitotic Cell Cycle Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Regulation Of DNA Replication Regulation Of Macrophage Activation Regulation Of Protein Metabolic Process Cell Cycle Telomere Maintenance Via Telomere Lengthening Cellular Response To Organic Substance Purine Nucleotide Biosynthetic Process Cell-matrix Adhesion Ribose Phosphate Biosynthetic Process Cellular Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Cellular Response To Acid Chemical	Protein Oligomerization Protein Complex Assembly Protein Homooligomerization Cellular Component Assembly Protein Homotetramerization Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Nucleoside Metabolic Process Catabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleoside Metabolic Process Anatomical Structure Development Small Molecule Metabolic Process Developmental Process Biosynthetic Process Cell Differentiation Nitrogen Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Apoptotic Process Cellular Metabolic Process Purine Nucleoside Monophosphate Catabolic Process Regulation Of Cell Death Tetrahydrobiopterin Biosynthetic Process Cell Development Nucleotide Metabolic Process System Development Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Ubiquitination Sulfur Amino Acid Metabolic Process Multicellular Organismal Development Aromatic Compound Catabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Modification By Small Protein Conjugation Cofactor Metabolic Process Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Neuron Projection Development Regulation Of Metabolic Process Organophosphate Metabolic Process Cellular Modified Amino Acid Metabolic Process Regulation Of Cellular Localization Membrane Organization Response To Stimulus Organophosphate Catabolic Process Double-strand Break Repair Cellular Process S-adenosylmethionine Metabolic Process Pyrimidine Nucleoside Metabolic Process
Tagcloud ?		17q12 anonymous brca1 cloning colia1 d17s183 dinucleotide edh17b exclude excludes families heterozygosity hox2 inherited locale ngfr nme2 ovarian phb pinpoint polymorphisms positional q21 rara recombination resolving scg43 thra1 wnt3
Tagcloud (Difference) ?		17q12 anonymous brca1 cloning colia1 d17s183 dinucleotide edh17b exclude excludes families heterozygosity hox2 inherited locale ngfr nme2 ovarian phb pinpoint polymorphisms positional q21 rara recombination resolving scg43 thra1 wnt3
Tagcloud (Intersection) ?