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NME1 and SREK1IP1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
NME1
SREK1IP1
Gene Name
NME/NM23 nucleoside diphosphate kinase 1
SREK1-interacting protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Membrane
Ruffle Membrane
Extracellular Vesicular Exosome
Molecular Function
Magnesium Ion Binding
Deoxyribonuclease Activity
Nucleoside Diphosphate Kinase Activity
Protein Binding
ATP Binding
GTP Binding
Identical Protein Binding
Ribosomal Small Subunit Binding
Poly(A) RNA Binding
Nucleic Acid Binding
Zinc Ion Binding
Biological Process
Purine Nucleotide Metabolic Process
Nucleoside Diphosphate Phosphorylation
GTP Biosynthetic Process
Pyrimidine Nucleotide Metabolic Process
UTP Biosynthetic Process
CTP Biosynthetic Process
DNA Catabolic Process
Endocytosis
Nervous System Development
Negative Regulation Of Cell Proliferation
Nucleoside Triphosphate Biosynthetic Process
Nucleobase-containing Small Molecule Interconversion
Cell Differentiation
Regulation Of Apoptotic Process
Positive Regulation Of DNA Binding
Small Molecule Metabolic Process
Positive Regulation Of Epithelial Cell Proliferation
Nucleobase-containing Small Molecule Metabolic Process
MRNA Processing
RNA Splicing
Pathways
Metabolism of nucleotides
Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS
Protein-Protein Interactions
27 interactors:
APEX1
AURKA
CCND3
FXR2
GORASP2
ITGB1
KSR1
MIF
NIF3L1
NME2
NME3
NME4
PID1
POLR1C
PRUNE
RAC1
RORA
RORB
RRAD
SET
SMARCD1
SOX30
SREK1IP1
TERF1
TIAM1
TNPO2
WDYHV1
8 interactors:
HSD17B14
NME1
PPCDC
RBM39
RP9P
SDCBP
SDCBP2
STAC3
Entrez ID
4830
285672
HPRD ID
01131
08210
Ensembl ID
ENSG00000239672
ENSG00000153006
Uniprot IDs
P15531
Q8N9Q2
PDB IDs
1JXV
1UCN
2HVD
2HVE
3L7U
4ENO
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cellular Metabolic Process
Regulation Of Apoptotic Process
GTP Biosynthetic Process
UTP Biosynthetic Process
GTP Metabolic Process
UTP Metabolic Process
Regulation Of Cell Death
CTP Biosynthetic Process
Positive Regulation Of Metabolic Process
Nucleoside Diphosphate Phosphorylation
Pyrimidine Ribonucleotide Biosynthetic Process
Pyrimidine Nucleoside Biosynthetic Process
Pyrimidine Nucleotide Biosynthetic Process
Nucleotide Phosphorylation
Nucleoside Diphosphate Metabolic Process
Regulation Of Metabolic Process
Response To Organic Cyclic Compound
Pyrimidine Nucleoside Metabolic Process
Regulation Of Cell Cycle
Response To Hormone
Pyrimidine Nucleotide Metabolic Process
Cellular Response To Lipid
Nucleoside Triphosphate Biosynthetic Process
Nucleosome Disassembly
Mitotic Cell Cycle
Nucleobase-containing Small Molecule Interconversion
Regulation Of Cell Cycle Process
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Cell Development
Response To Drug
Positive Regulation Of Cell Projection Organization
Response To Organic Substance
Positive Regulation Of Cell Cycle
Response To Lipid
Ribonucleotide Metabolic Process
Positive Regulation Of Mitotic Cell Cycle
Purine Nucleotide Metabolic Process
Ribose Phosphate Metabolic Process
Regulation Of DNA Replication
Regulation Of Macrophage Activation
Regulation Of Protein Metabolic Process
Cell Cycle
Telomere Maintenance Via Telomere Lengthening
Cellular Response To Organic Substance
Purine Nucleotide Biosynthetic Process
Cell-matrix Adhesion
Ribose Phosphate Biosynthetic Process
Cellular Response To Organic Cyclic Compound
Regulation Of Cellular Component Organization
Cellular Response To Acid Chemical
Purine Nucleotide Biosynthetic Process
Ribose Phosphate Biosynthetic Process
Positive Regulation Of Extracellular Vesicular Exosome Assembly
Regulation Of Extracellular Vesicular Exosome Assembly
Purine Nucleoside Metabolic Process
Ribonucleotide Metabolic Process
Nucleoside Metabolic Process
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Nucleotide Biosynthetic Process
Purine Nucleotide Metabolic Process
Substrate-dependent Cell Migration, Cell Extension
Pantothenate Metabolic Process
Ribose Phosphate Metabolic Process
Nucleobase-containing Small Molecule Interconversion
Coenzyme A Biosynthetic Process
Skeletal Muscle Fiber Development
Steroid Catabolic Process
Tagcloud
?
17q12
anonymous
brca1
cloning
colia1
d17s183
dinucleotide
edh17b
exclude
excludes
families
heterozygosity
hox2
inherited
locale
ngfr
nme2
ovarian
phb
pinpoint
polymorphisms
positional
q21
rara
recombination
resolving
scg43
thra1
wnt3
Tagcloud (Difference)
?
17q12
anonymous
brca1
cloning
colia1
d17s183
dinucleotide
edh17b
exclude
excludes
families
heterozygosity
hox2
inherited
locale
ngfr
nme2
ovarian
phb
pinpoint
polymorphisms
positional
q21
rara
recombination
resolving
scg43
thra1
wnt3
Tagcloud (Intersection)
?