NME1 and SOX30

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NME1	SOX30
Gene Name		NME/NM23 nucleoside diphosphate kinase 1	SRY (sex determining region Y)-box 30
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Ruffle Membrane Extracellular Vesicular Exosome	Nucleus
	Molecular Function	Magnesium Ion Binding Deoxyribonuclease Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Ribosomal Small Subunit Binding Poly(A) RNA Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Catabolic Process Endocytosis Nervous System Development Negative Regulation Of Cell Proliferation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Cell Differentiation Regulation Of Apoptotic Process Positive Regulation Of DNA Binding Small Molecule Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Nucleobase-containing Small Molecule Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Spermatogenesis Response To Corticosteroid
Pathways		Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APEX1 AURKA CCND3 FXR2 GORASP2 ITGB1 KSR1 MIF NIF3L1 NME2 NME3 NME4 PID1 POLR1C PRUNE RAC1 RORA RORB RRAD SET SMARCD1 SOX30 SREK1IP1 TERF1 TIAM1 TNPO2 WDYHV1	16 interactors: AHCYL1 BAMBI BRCA1 C6orf165 CUL5 DCAF4 DDX56 FBXO38 FLI1 GNAI3 GP2 KIFC3 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		4830	11063
HPRD ID		01131	09461
Ensembl ID		ENSG00000239672	ENSG00000039600
Uniprot IDs		P15531	B4DXW7 O94993
PDB IDs		1JXV 1UCN 2HVD 2HVE 3L7U 4ENO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process Regulation Of Cell Death CTP Biosynthetic Process Positive Regulation Of Metabolic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Regulation Of Metabolic Process Response To Organic Cyclic Compound Pyrimidine Nucleoside Metabolic Process Regulation Of Cell Cycle Response To Hormone Pyrimidine Nucleotide Metabolic Process Cellular Response To Lipid Nucleoside Triphosphate Biosynthetic Process Nucleosome Disassembly Mitotic Cell Cycle Nucleobase-containing Small Molecule Interconversion Regulation Of Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Development Response To Drug Positive Regulation Of Cell Projection Organization Response To Organic Substance Positive Regulation Of Cell Cycle Response To Lipid Ribonucleotide Metabolic Process Positive Regulation Of Mitotic Cell Cycle Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Regulation Of DNA Replication Regulation Of Macrophage Activation Regulation Of Protein Metabolic Process Cell Cycle Telomere Maintenance Via Telomere Lengthening Cellular Response To Organic Substance Purine Nucleotide Biosynthetic Process Cell-matrix Adhesion Ribose Phosphate Biosynthetic Process Cellular Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Cellular Response To Acid Chemical	Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Binding Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Histone Methylation Protein Ubiquitination Protein Autoubiquitination Regulation Of Histone Acetylation Protein Modification By Small Protein Conjugation Regulation Of Histone Methylation Regulation Of Binding Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Positive Regulation Of Histone H4-K16 Acetylation Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Protein Binding Positive Regulation Of Histone Modification DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H3-K9 Acetylation Signal Transduction In Response To DNA Damage Cellular Response To Tumor Necrosis Factor Zonula Adherens Maintenance Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Response To Tumor Necrosis Factor Positive Regulation Of Protein Ubiquitination S-adenosylmethionine Cycle Cellular Response To Indole-3-methanol Response To Ionizing Radiation Regulation Of Protein Binding Positive Regulation Of DNA Metabolic Process Negative Regulation Of Centriole Replication Positive Regulation Of Adaptive Immune Response Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Glial Cell Apoptotic Process Protein Polyubiquitination Protein K6-linked Ubiquitination Chorion Development Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Intrinsic Apoptotic Signaling Pathway Nucleobase-containing Small Molecule Metabolic Process
Tagcloud ?		17q12 anonymous brca1 cloning colia1 d17s183 dinucleotide edh17b exclude excludes families heterozygosity hox2 inherited locale ngfr nme2 ovarian phb pinpoint polymorphisms positional q21 rara recombination resolving scg43 thra1 wnt3	activating advance antitumorigenic attenuates blockade box cactttg doi ectopic harboring hypermethylated hypermethylation indeed lung methylated onc oncogene online peri preferentially publication represses silence silenced sry tumoral unexplored unmethylated
Tagcloud (Difference) ?		17q12 anonymous brca1 cloning colia1 d17s183 dinucleotide edh17b exclude excludes families heterozygosity hox2 inherited locale ngfr nme2 ovarian phb pinpoint polymorphisms positional q21 rara recombination resolving scg43 thra1 wnt3	activating advance antitumorigenic attenuates blockade box cactttg doi ectopic harboring hypermethylated hypermethylation indeed lung methylated onc oncogene online peri preferentially publication represses silence silenced sry tumoral unexplored unmethylated
Tagcloud (Intersection) ?