NME1 and NME3

Number of citations of the paper that reports this interaction (PubMedID 11042679)
0

Data Source:
HPRD (in vivo)

		NME1	NME3
Description		NME/NM23 nucleoside diphosphate kinase 1	NME/NM23 nucleoside diphosphate kinase 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Cytosol Membrane Ruffle Membrane Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Cytoskeleton Membrane Ciliary Basal Body Cell Projection
	Molecular Function	Nucleotide Binding Magnesium Ion Binding DNA Binding RNA Binding DNA Endonuclease Activity DNA Nuclease Activity Nucleoside Diphosphate Kinase Activity Protein Histidine Kinase Activity Protein Binding ATP Binding 3'-5'-DNA Exonuclease Activity Kinase Activity Transferase Activity Phosphotransferase Activity, Phosphate Group As Acceptor GDP Binding Identical Protein Binding Ribosomal Small Subunit Binding ADP Binding Metal Ion Binding Farnesyl Diphosphate Kinase Activity Coenzyme A Binding Succinyl-CoA Binding Acetyl-CoA Binding	Nucleotide Binding Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity GDP Binding CAMP Binding ADP Binding Metal Ion Binding Phosphatidic Acid Binding Mitochondrion-mitochondrion Outer Membrane Tether Activity
	Biological Process	GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Catabolic Process Apoptotic DNA Fragmentation Isoprenoid Metabolic Process Endocytosis Nervous System Development Lactation Negative Regulation Of Cell Population Proliferation Nucleotide Metabolic Process Nucleoside Diphosphate Metabolic Process Nucleoside Triphosphate Biosynthetic Process Cell Differentiation Mammary Gland Development Protein Hexamerization Regulation Of Fatty Acid Biosynthetic Process Regulation Of Apoptotic Process ITP Biosynthetic Process Acetyl-CoA Catabolic Process Positive Regulation Of Epithelial Cell Proliferation	GTP Biosynthetic Process UTP Biosynthetic Process DTTP Biosynthetic Process CTP Biosynthetic Process DNA Repair Apoptotic Process Mitochondrial Fusion Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Protein Hexamerization Mitochondrial Outer Membrane Fusion
Pathways		Interconversion of nucleotide di- and triphosphates Azathioprine ADME Ribavirin ADME	Interconversion of nucleotide di- and triphosphates
Drugs		Zinc 2'-Deoxyguanosine-5'-Triphosphate Selenocysteine 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate Adenosine Phosphonoacetic Acid Stavudine triphosphate Thymidine-5'- Diphosphate 2'-Deoxyguanosine-5'-Diphosphate 2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate Guanosine-5'-Diphosphate 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate Zidovudine diphosphate Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Bipolar disorder ( 31043756) Conjunctival UV autofluorescence (CUVAF) ( 25590795) Metabolite levels ( 23823483)
Interacting Genes		35 interacting genes: APEX1 AURKA CCND3 DDX19A FBXO24 FXR1 FXR2 GORASP2 ITGB1 KSR1 LNX1 MIF NIF3L1 NME3 NME4 NTAQ1 NUTF2 NXF1 PID1 POLR1C PRPF6 PRUNE1 RAC1 RORA RORB RRAD SET SMARCD1 SNCA SOX30 SREK1IP1 TERF1 TIAM1 TNPO2 TNPO3	13 interacting genes: APP DESI1 FXR1 FXR2 HTR2A JAM2 NME1 NME2 SGTA SGTB UBQLN1 UBQLN2 UBQLN4
Entrez ID		4830	4832
HPRD ID		01131	03488
Ensembl ID		ENSG00000239672	ENSG00000103024
Uniprot IDs		A0A384MTW7 P15531	Q13232
PDB IDs		1JXV 1UCN 2HVD 2HVE 3L7U 4ENO 5UI4 8OOV	1ZS6 8QVY 8QVZ 8QW0 8QW1 8QW2 8QW3
Enriched GO Terms of Interacting Partners?		Mitochondrion-mitochondrion Outer Membrane Tether Activity Regulation Of Neuronal Synaptic Plasticity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission MRNA Transport RNA Transport Nuclear Import Signal Receptor Activity Regulation Of Long-term Neuronal Synaptic Plasticity Cytoplasmic Stress Granule Cytoplasm Nucleobase-containing Compound Transport Negative Regulation Of Biosynthetic Process Postsynapse Double-stranded Telomeric DNA Binding Cellular Component Assembly UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Nuclear Transport Nucleocytoplasmic Transport Regulation Of Cell Differentiation Central Nervous System Neuron Differentiation Protein Hexamerization Protein Binding Regulation Of Cell Development Regulation Of Macrophage Activation Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cell Development CTP Biosynthetic Process CTP Metabolic Process Regulation Of Microtubule Polymerization Protein-containing Complex Organization Nucleoside Diphosphate Kinase Activity Regulation Of Hydrogen Peroxide Metabolic Process Nucleus Translation Regulator Activity Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Cytoplasmic Ribonucleoprotein Granule Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Neurotransmitter Uptake Neuron Differentiation Protein-containing Complex Assembly Regulation Of Synaptic Plasticity Nucleosome Disassembly Regulation Of Rho Protein Signal Transduction Regulation Of Neurogenesis GTP Metabolic Process Regulation Of Cell Maturation Protein-DNA Complex Disassembly	Identical Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Catabolic Process Regulation Of Proteolysis Regulation Of Protein Catabolic Process Positive Regulation Of ERAD Pathway Regulation Of Proteasomal Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress ITP Biosynthetic Process Protein Histidine Kinase Activity TRC Complex Regulation Of ERAD Pathway Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Protein Metabolic Process ITP Metabolic Process Polyubiquitin Modification-dependent Protein Binding Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Presynapse Regulation Of Cellular Response To Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Autophagosome Negative Regulation Of Long-term Synaptic Potentiation CTP Biosynthetic Process CTP Metabolic Process Regulation Of Primary Metabolic Process ERAD Pathway Nucleoside Diphosphate Kinase Activity Positive Regulation Of Proteasomal Protein Catabolic Process Translation Regulator Activity Perinuclear Region Of Cytoplasm GTP Metabolic Process Positive Regulation Of Glycolytic Process Pyrimidine Ribonucleotide Biosynthetic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Dentate Gyrus Development Protein Targeting To ER Pyrimidine Nucleotide Biosynthetic Process Cytoplasmic Vesicle Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cell Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?