NFIX and JMJD6

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		NFIX	JMJD6
Gene Name		nuclear factor I/X (CCAAT-binding transcription factor)	jumonji domain containing 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity	RNA Binding Single-stranded RNA Binding Receptor Activity Iron Ion Binding Protein Binding Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Transcription From RNA Polymerase II Promoter Cerebellar Purkinje Cell Layer Development Cerebellar Granule Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Astrocyte Differentiation	Kidney Development Sprouting Angiogenesis Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Macrophage Activation Recognition Of Apoptotic Cell Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Oxidation-reduction Process Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS			Retinal arteriolar caliber ( 23776548)
Protein-Protein Interactions		7 interactors: JMJD6 NFIB PIR QRICH1 RFX1 SKI ZNF614	28 interactors: AEBP2 ANKEF1 BRD4 C17orf97 CCNL1 CENPL DIP2A FAM9A FGD5 FRMD6 GNA14 HIST1H2BJ HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 RSRC1 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZCCHC17 ZNF451
Entrez ID		4784	23210
HPRD ID		01234	05371
Ensembl ID		ENSG00000008441	ENSG00000070495
Uniprot IDs		B4DHW2 D2DXM9 Q14938	Q6NYC1
PDB IDs			3K2O 3LD8 3LDB
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Respiratory System Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of DNA Binding Lung Ciliated Cell Differentiation Histone H3-R2 Demethylation Histone H4-R3 Demethylation Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Principal Sensory Nucleus Of Trigeminal Nerve Development Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Tube Development Nose Morphogenesis Nitrogen Compound Metabolic Process Retina Development In Camera-type Eye Glial Cell Differentiation Negative Regulation Of Histone Deacetylation Negative Regulation Of Schwann Cell Proliferation Negative Regulation Of Mesenchymal Cell Proliferation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Gliogenesis Recognition Of Apoptotic Cell Type II Pneumocyte Differentiation Clara Cell Differentiation Myeloid Cell Differentiation Lung Development Respiratory Tube Development Regulation Of Binding Anterior Commissure Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Telencephalon Development Negative Regulation Of Glial Cell Proliferation Leukocyte Differentiation Lung Secretory Cell Differentiation	Chromatin Organization RNA Processing RNA Metabolic Process Gene Expression Chromosome Organization Alternative MRNA Splicing, Via Spliceosome Nucleosome Assembly Chromatin Modification Cellular Nitrogen Compound Metabolic Process Chromatin Assembly RNA Splicing Nucleosome Organization Chromatin Assembly Or Disassembly G1/S Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Protein-DNA Complex Assembly Mitotic Cell Cycle MRNA Processing Chromatin Remodeling DNA Packaging Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Sister Chromatid Cohesion, Centromeric RRNA Pseudouridine Synthesis Histone H4 Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Regulation Of Wnt Signaling Pathway Cellular Macromolecular Complex Assembly Negative Regulation Of DNA Damage Checkpoint Apical Constriction Lung Growth Histone H3-K14 Acetylation Mitotic Cell Cycle Process MRNA 3'-splice Site Recognition Transcription, DNA-templated Histone Acetylation Trachea Cartilage Morphogenesis Internal Peptidyl-lysine Acetylation Positive Regulation Of Canonical Wnt Signaling Pathway Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation
Tagcloud ?		aluy anomalies cleared craniofacial decay difficulties dimerization dysfunctional encode exon frameshift grossly homogeneous intron ligation malformation marshall mendelian mss multiplex nonsense osseous portion preserved recurrent smith splice thrive vary	acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65
Tagcloud (Difference) ?		aluy anomalies cleared craniofacial decay difficulties dimerization dysfunctional encode frameshift grossly homogeneous intron ligation malformation marshall mendelian mss multiplex nonsense osseous portion preserved recurrent smith thrive vary	acinus arginine auxiliary bona definition exerts fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splicing sr srsf1 srsf11 u2 u2af65
Tagcloud (Intersection) ?		exon splice