NFIX and PIR

Number of citations of the paper that reports this interaction (PubMedID 9079676)
0

Data Source:
HPRD (two hybrid, in vivo)

		NFIX	PIR
Description		nuclear factor I X	pirin
Image
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Coregulator Activity Protein Binding Quercetin 2,3-dioxygenase Activity Oxidoreductase Activity Metal Ion Binding Dioxygenase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Digestion Myeloid Cell Differentiation Monocyte Differentiation
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	Digestion
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Body mass index ( 25673413) Brain morphology (MOSTest) ( 32665545) Clozapine-induced agranulocytosis ( 25187353) Cortical surface area ( 32963231) Cortical volume ( 32963231) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemoglobin ( 32888494) Hip index ( 34021172) Intelligence (MTAG) ( 29326435) Lymphocyte count ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		24 interacting genes: JMJD6 LHX4 NFIB PAX2 PAX6 PAX7 PAX8 PIR PRDM1 QRICH1 RFX1 SKI SOX10 SOX15 SOX17 SOX5 SOX6 SOX9 SP7 TBR1 TLX2 TLX3 YY1 ZNF614	4 interacting genes: BCL3 NFIX NFKBIA SMAD9
Entrez ID		4784	8544
HPRD ID		01234	04510
Ensembl ID		ENSG00000008441	ENSG00000087842
Uniprot IDs		B4DHW2 D2DXM9 Q14938	O00625
PDB IDs		7QQD 7QQE	1J1L 3ACL 4ERO 4EWA 4EWD 4EWE 4GUL 4HLT 5JCT 6H1H 6H1I 6N0J 6N0K
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding Chromatin DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Animal Organ Development Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Cis-regulatory Region Binding Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Cellular Developmental Process Positive Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Positive Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Metanephric Nephron Tubule Formation Regulation Of Gene Expression Cell Fate Commitment Gene Expression Regulation Of Macromolecule Biosynthetic Process Glial Cell Differentiation Negative Regulation Of Developmental Process Metanephric Tubule Formation Positive Regulation Of Mesenchymal Stem Cell Differentiation Regulation Of Macromolecule Metabolic Process Lacrimal Gland Development Developmental Process Glial Cell Fate Specification Ureter Development Regulation Of Developmental Process Regulation Of Cell Differentiation Neuron Differentiation Positive Regulation Of Macromolecule Metabolic Process Retina Development In Camera-type Eye Regulation Of Stem Cell Differentiation Pattern Specification Process Regionalization	Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Canonical NF-kappaB Signal Transduction Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Bcl3-Bcl10 Complex Protein Import Into Nucleus Import Into Nucleus Bcl3/NF-kappaB2 Complex Intracellular Signaling Cassette Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Follicular Dendritic Cell Differentiation Positive Regulation Of Biosynthetic Process Regulation Of DNA-binding Transcription Factor Activity Protein Localization To Nucleus Follicular Dendritic Cell Activation I-kappaB/NF-kappaB Complex Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of RNA Biosynthetic Process Nuclear Transport Nucleocytoplasmic Transport Positive Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process SMAD Protein Complex Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Heteromeric SMAD Protein Complex Germinal Center Formation Regulation Of Nucleobase-containing Compound Metabolic Process T-helper 2 Cell Differentiation Negative Regulation Of RNA Metabolic Process Marginal Zone B Cell Differentiation Negative Regulation Of Cytokine Production T-helper 1 Type Immune Response Establishment Of Protein Localization To Organelle Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Negative Regulation Of Macrophage Derived Foam Cell Differentiation Response To UV-C Cellular Response To Cold I-SMAD Binding Intracellular Signal Transduction Negative Regulation Of Protein Import Into Nucleus
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