NFIX and PIR

Number of citations of the paper that reports this interaction (PMID 9079676)
20

Data Source:
HPRD (two hybrid, in vivo)

		NFIX	PIR
Gene Name		nuclear factor I/X (CCAAT-binding transcription factor)	pirin (iron-binding nuclear protein)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity	Transcription Cofactor Activity Protein Binding Quercetin 2,3-dioxygenase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Transcription From RNA Polymerase II Promoter Cerebellar Purkinje Cell Layer Development Cerebellar Granule Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Astrocyte Differentiation	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Monocyte Differentiation Oxidation-reduction Process
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: JMJD6 NFIB PIR QRICH1 RFX1 SKI ZNF614	4 interactors: BCL3 NFIX NFKBIA SMAD9
Entrez ID		4784	8544
HPRD ID		01234	04510
Ensembl ID		ENSG00000008441	ENSG00000087842
Uniprot IDs		B4DHW2 D2DXM9 Q14938	O00625
PDB IDs			1J1L 3ACL 4ERO 4EWA 4EWD 4EWE 4GUL 4HLT
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Respiratory System Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of DNA Binding Lung Ciliated Cell Differentiation Histone H3-R2 Demethylation Histone H4-R3 Demethylation Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Principal Sensory Nucleus Of Trigeminal Nerve Development Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Tube Development Nose Morphogenesis Nitrogen Compound Metabolic Process Retina Development In Camera-type Eye Glial Cell Differentiation Negative Regulation Of Histone Deacetylation Negative Regulation Of Schwann Cell Proliferation Negative Regulation Of Mesenchymal Cell Proliferation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Gliogenesis Recognition Of Apoptotic Cell Type II Pneumocyte Differentiation Clara Cell Differentiation Myeloid Cell Differentiation Lung Development Respiratory Tube Development Regulation Of Binding Anterior Commissure Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Telencephalon Development Negative Regulation Of Glial Cell Proliferation Leukocyte Differentiation Lung Secretory Cell Differentiation	Protein Import Into Nucleus, Translocation Positive Regulation Of Transcription, DNA-templated Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of DNA Binding Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Cellular Metabolic Process Protein Import Into Nucleus Nuclear Import Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Protein Import Regulation Of Protein Import Into Nucleus Protein Localization To Nucleus Hindbrain Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Positive Regulation Of Interleukin-10 Biosynthetic Process Response To Abiotic Stimulus Regulation Of Protein Localization To Nucleus Positive Regulation Of Metabolic Process Regulation Of Nucleocytoplasmic Transport Regulation Of I-kappaB Kinase/NF-kappaB Signaling Follicular Dendritic Cell Differentiation T-helper 2 Cell Differentiation Regulation Of Binding Regulation Of Intracellular Protein Transport Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Interleukin-8 Biosynthetic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Marginal Zone B Cell Differentiation Cytoplasmic Sequestering Of NF-kappaB Cellular Response To Cold Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mullerian Duct Regression Establishment Of Protein Localization To Organelle Regulation Of RNA Metabolic Process Positive Regulation Of Cytokine Production Type 2 Immune Response Protein Targeting Intracellular Signal Transduction Regulation Of Gene Expression
Tagcloud ?		aluy anomalies cleared craniofacial decay difficulties dimerization dysfunctional encode exon frameshift grossly homogeneous intron ligation malformation marshall mendelian mss multiplex nonsense osseous portion preserved recurrent smith splice thrive vary	125i alpha2 blast cleave columns conditioned dependently digest facilitating film gccm genbank germ homogeneity hydrolyzing intertesticular junction kda kyefyeixll macroglobulin nh2 postulated protease proteolysis secretory sertoli testes testin tryptic
Tagcloud (Difference) ?		aluy anomalies cleared craniofacial decay difficulties dimerization dysfunctional encode exon frameshift grossly homogeneous intron ligation malformation marshall mendelian mss multiplex nonsense osseous portion preserved recurrent smith splice thrive vary	125i alpha2 blast cleave columns conditioned dependently digest facilitating film gccm genbank germ homogeneity hydrolyzing intertesticular junction kda kyefyeixll macroglobulin nh2 postulated protease proteolysis secretory sertoli testes testin tryptic
Tagcloud (Intersection) ?