JMJD6 and TAF1A

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		JMJD6	TAF1A
Gene Name		jumonji domain containing 6	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Plasma Membrane	RNA Polymerase I Transcription Factor Complex Nucleus Nucleoplasm Microtubule Cytoskeleton Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Single-stranded RNA Binding Receptor Activity Iron Ion Binding Protein Binding Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity	DNA Binding Protein Binding
	Biological Process	Kidney Development Sprouting Angiogenesis Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Macrophage Activation Recognition Of Apoptotic Cell Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Oxidation-reduction Process Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation	Chromatin Silencing At RDNA Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways			NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression SIRT1 negatively regulates rRNA Expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS		Retinal arteriolar caliber ( 23776548)
Protein-Protein Interactions		28 interactors: AEBP2 ANKEF1 BRD4 C17orf97 CCNL1 CENPL DIP2A FAM9A FGD5 FRMD6 GNA14 HIST1H2BJ HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 RSRC1 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZCCHC17 ZNF451	21 interactors: ANP32A C11orf57 CD3EAP ESR1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE HIST3H3 HIST4H4 JMJD6 RRN3 RUNX2 SET TAF12 TAF1B TAF1C TAF1D TBP TP53 UBTF
Entrez ID		23210	9015
HPRD ID		05371	05362
Ensembl ID		ENSG00000070495	ENSG00000143498
Uniprot IDs		Q6NYC1	A8K4K5 B4DS21 Q15573
PDB IDs		3K2O 3LD8 3LDB
Enriched GO Terms of Interacting Partners?		Chromatin Organization RNA Processing RNA Metabolic Process Gene Expression Chromosome Organization Alternative MRNA Splicing, Via Spliceosome Nucleosome Assembly Chromatin Modification Cellular Nitrogen Compound Metabolic Process Chromatin Assembly RNA Splicing Nucleosome Organization Chromatin Assembly Or Disassembly G1/S Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Protein-DNA Complex Assembly Mitotic Cell Cycle MRNA Processing Chromatin Remodeling DNA Packaging Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Sister Chromatid Cohesion, Centromeric RRNA Pseudouridine Synthesis Histone H4 Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Regulation Of Wnt Signaling Pathway Cellular Macromolecular Complex Assembly Negative Regulation Of DNA Damage Checkpoint Apical Constriction Lung Growth Histone H3-K14 Acetylation Mitotic Cell Cycle Process MRNA 3'-splice Site Recognition Transcription, DNA-templated Histone Acetylation Trachea Cartilage Morphogenesis Internal Peptidyl-lysine Acetylation Positive Regulation Of Canonical Wnt Signaling Pathway Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation	Chromatin Silencing At RDNA Negative Regulation Of Gene Expression, Epigenetic Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Chromatin Silencing DNA-templated Transcription, Initiation Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Elongation Gene Silencing Negative Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Termination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Organization Cellular Nitrogen Compound Metabolic Process Chromosome Organization Nitrogen Compound Metabolic Process Chromatin Assembly Regulation Of Gene Expression Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein-DNA Complex Assembly RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Packaging Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nucleosome Assembly Cellular Macromolecule Biosynthetic Process DNA Replication-dependent Nucleosome Assembly Macromolecule Biosynthetic Process DNA Conformation Change Nucleosome Organization RNA Metabolic Process DNA Methylation On Cytosine RRNA Transcription Regulation Of Metabolic Process Organelle Organization Biosynthetic Process Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1b taf1c tata tbp tumourigenesis ubf
Tagcloud (Difference) ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1b taf1c tata tbp tumourigenesis ubf
Tagcloud (Intersection) ?