JMJD6 and GNA14

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		JMJD6	GNA14
Gene Name		jumonji domain containing 6	guanine nucleotide binding protein (G protein), alpha 14
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Plasma Membrane	Heterotrimeric G-protein Complex Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Single-stranded RNA Binding Receptor Activity Iron Ion Binding Protein Binding Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity	G-protein Coupled Receptor Binding GTPase Activity Signal Transducer Activity GTP Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	Kidney Development Sprouting Angiogenesis Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Macrophage Activation Recognition Of Apoptotic Cell Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Oxidation-reduction Process Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation	Signal Transduction Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Blood Coagulation Platelet Activation Phospholipase C-activating Dopamine Receptor Signaling Pathway
Pathways			G alpha (q) signalling events Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Signaling by GPCR ADP signalling through P2Y purinoceptor 1 Integration of energy metabolism Regulation of insulin secretion Signal amplification Thrombin signalling through proteinase activated receptors (PARs) G alpha (q) signalling events GPCR downstream signaling Acetylcholine regulates insulin secretion Gastrin-CREB signalling pathway via PKC and MAPK Thromboxane signalling through TP receptor Platelet activation, signaling and aggregation Free fatty acids regulate insulin secretion
Drugs
Diseases
GWAS		Retinal arteriolar caliber ( 23776548)
Protein-Protein Interactions		28 interactors: AEBP2 ANKEF1 BRD4 C17orf97 CCNL1 CENPL DIP2A FAM9A FGD5 FRMD6 GNA14 HIST1H2BJ HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 RSRC1 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZCCHC17 ZNF451	9 interactors: ADRB2 CCR1 CHRM2 CXCR1 CXCR2 DNAL4 JMJD6 OPRL1 SSTR2
Entrez ID		23210	9630
HPRD ID		05371	05095
Ensembl ID		ENSG00000070495	ENSG00000156049
Uniprot IDs		Q6NYC1	B1ALW3 O95837
PDB IDs		3K2O 3LD8 3LDB
Enriched GO Terms of Interacting Partners?		Chromatin Organization RNA Processing RNA Metabolic Process Gene Expression Chromosome Organization Alternative MRNA Splicing, Via Spliceosome Nucleosome Assembly Chromatin Modification Cellular Nitrogen Compound Metabolic Process Chromatin Assembly RNA Splicing Nucleosome Organization Chromatin Assembly Or Disassembly G1/S Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Protein-DNA Complex Assembly Mitotic Cell Cycle MRNA Processing Chromatin Remodeling DNA Packaging Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Sister Chromatid Cohesion, Centromeric RRNA Pseudouridine Synthesis Histone H4 Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Regulation Of Wnt Signaling Pathway Cellular Macromolecular Complex Assembly Negative Regulation Of DNA Damage Checkpoint Apical Constriction Lung Growth Histone H3-K14 Acetylation Mitotic Cell Cycle Process MRNA 3'-splice Site Recognition Transcription, DNA-templated Histone Acetylation Trachea Cartilage Morphogenesis Internal Peptidyl-lysine Acetylation Positive Regulation Of Canonical Wnt Signaling Pathway Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation	G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Surface Receptor Signaling Pathway Dendritic Cell Chemotaxis G-protein Coupled Receptor Signaling Pathway Dendritic Cell Migration Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Interleukin-8-mediated Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Chemokine-mediated Signaling Pathway Signal Transduction Signaling Homeostatic Process Cellular Calcium Ion Homeostasis Cell Communication Calcium Ion Homeostasis Leukocyte Chemotaxis Cellular Metal Ion Homeostasis Cellular Response To Stimulus Cellular Cation Homeostasis Response To External Stimulus Cellular Ion Homeostasis Metal Ion Homeostasis Cell Chemotaxis Cellular Chemical Homeostasis Ion Homeostasis Endocytosis Leukocyte Migration Response To Stimulus Cellular Homeostasis Vesicle-mediated Transport Receptor Internalization Chemical Homeostasis Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Receptor-mediated Endocytosis Positive Regulation Of Leukocyte Chemotaxis Cellular Response To Organic Substance Regulation Of Bone Mineralization Negative Regulation Of Neutrophil Apoptotic Process Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Receptor Metabolic Process Inflammatory Response Positive Regulation Of Leukocyte Migration Cytokine-mediated Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Chemotaxis
Tagcloud ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 involvements jmjd1c nrbf2 parp8 pla2g4a rhog rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2
Tagcloud (Difference) ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 involvements jmjd1c nrbf2 parp8 pla2g4a rhog rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2
Tagcloud (Intersection) ?