NFIB and NFIX

Number of citations of the paper that reports this interaction (PMID 9099724)
9

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		NFIB	NFIX
Gene Name		nuclear factor I/B	nuclear factor I/X (CCAAT-binding transcription factor)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cerebellar Mossy Fiber	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Corepressor Activity DNA Binding Double-stranded DNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chondrocyte Differentiation DNA Replication Transcription From RNA Polymerase II Promoter Glial Cell Differentiation Principal Sensory Nucleus Of Trigeminal Nerve Development Anterior Commissure Morphogenesis Hindbrain Development Negative Regulation Of DNA Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter Clara Cell Differentiation Type I Pneumocyte Differentiation Type II Pneumocyte Differentiation Lung Ciliated Cell Differentiation Commissural Neuron Axon Guidance Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Transcription From RNA Polymerase II Promoter Cerebellar Purkinje Cell Layer Development Cerebellar Granule Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Astrocyte Differentiation
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation	RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23419831)
Protein-Protein Interactions		3 interactors: NFIC NFIX RFX1	7 interactors: JMJD6 NFIB PIR QRICH1 RFX1 SKI ZNF614
Entrez ID		4781	4784
HPRD ID		09008	01234
Ensembl ID		ENSG00000147862	ENSG00000008441
Uniprot IDs		O00712 Q5VW26 Q5VW27 Q5VW28 Q5VW30	B4DHW2 D2DXM9 Q14938
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter DNA Replication Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Cerebellar Granule Cell Differentiation Cerebellar Granular Layer Morphogenesis RNA Metabolic Process Cerebellar Granular Layer Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cerebellar Cortex Formation Cellular Macromolecule Biosynthetic Process Cell Differentiation In Hindbrain Macromolecule Biosynthetic Process Cerebellar Purkinje Cell Layer Development Astrocyte Differentiation Cerebellar Cortex Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Cerebellum Morphogenesis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Hindbrain Morphogenesis Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cerebellar Cortex Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Odontogenesis Of Dentin-containing Tooth Cerebellum Development Metencephalon Development Odontogenesis Hindbrain Development Negative Regulation Of Cellular Metabolic Process	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Respiratory System Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of DNA Binding Lung Ciliated Cell Differentiation Histone H3-R2 Demethylation Histone H4-R3 Demethylation Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Principal Sensory Nucleus Of Trigeminal Nerve Development Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Tube Development Nose Morphogenesis Nitrogen Compound Metabolic Process Retina Development In Camera-type Eye Glial Cell Differentiation Negative Regulation Of Histone Deacetylation Negative Regulation Of Schwann Cell Proliferation Negative Regulation Of Mesenchymal Cell Proliferation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Gliogenesis Recognition Of Apoptotic Cell Type II Pneumocyte Differentiation Clara Cell Differentiation Myeloid Cell Differentiation Lung Development Respiratory Tube Development Regulation Of Binding Anterior Commissure Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Telencephalon Development Negative Regulation Of Glial Cell Proliferation Leukocyte Differentiation Lung Secretory Cell Differentiation
Tagcloud ?		abolished aimed alteration caused colony direct dyrk1a explore finding fluorescent hcc hepatocellular hepg2 mir modulated nfat oncogene overexpression p53 propose regulated reporter suggests suppresses syndrome target targeting tumorigenesis wild	aluy anomalies cleared craniofacial decay difficulties dimerization dysfunctional encode exon frameshift grossly homogeneous intron ligation malformation marshall mendelian mss multiplex nonsense osseous portion preserved recurrent smith splice thrive vary
Tagcloud (Difference) ?		abolished aimed alteration caused colony direct dyrk1a explore finding fluorescent hcc hepatocellular hepg2 mir modulated nfat oncogene overexpression p53 propose regulated reporter suggests suppresses syndrome target targeting tumorigenesis wild	aluy anomalies cleared craniofacial decay difficulties dimerization dysfunctional encode exon frameshift grossly homogeneous intron ligation malformation marshall mendelian mss multiplex nonsense osseous portion preserved recurrent smith splice thrive vary
Tagcloud (Intersection) ?