NFIB

Gene Name		nuclear factor I/B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cerebellar Mossy Fiber
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Corepressor Activity DNA Binding Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chondrocyte Differentiation DNA Replication Transcription From RNA Polymerase II Promoter Glial Cell Differentiation Principal Sensory Nucleus Of Trigeminal Nerve Development Anterior Commissure Morphogenesis Hindbrain Development Negative Regulation Of DNA Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter Clara Cell Differentiation Type I Pneumocyte Differentiation Type II Pneumocyte Differentiation Lung Ciliated Cell Differentiation Commissural Neuron Axon Guidance Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23419831)
Protein-protein Interactions		3 interactors: NFIC NFIX RFX1
Entrez ID		4781
HPRD ID		09008
Ensembl ID		ENSG00000147862
Uniprot IDs		O00712 Q5VW26 Q5VW27 Q5VW28 Q5VW30
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter DNA Replication Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Cerebellar Granule Cell Differentiation Cerebellar Granular Layer Morphogenesis RNA Metabolic Process Cerebellar Granular Layer Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cerebellar Cortex Formation Cellular Macromolecule Biosynthetic Process Cell Differentiation In Hindbrain Macromolecule Biosynthetic Process Cerebellar Purkinje Cell Layer Development Astrocyte Differentiation Cerebellar Cortex Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Cerebellum Morphogenesis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Hindbrain Morphogenesis Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cerebellar Cortex Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Odontogenesis Of Dentin-containing Tooth Cerebellum Development Metencephalon Development Odontogenesis Hindbrain Development Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		abolished aimed alteration caused colony direct dyrk1a explore finding fluorescent hcc hepatocellular hepg2 mir modulated nfat oncogene overexpression p53 propose regulated reporter suggests suppresses syndrome target targeting tumorigenesis wild