NFIB and RFX1

Number of citations of the paper that reports this interaction (PMID 12624117)
3

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		NFIB	RFX1
Gene Name		nuclear factor I/B	regulatory factor X, 1 (influences HLA class II expression)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cerebellar Mossy Fiber	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Corepressor Activity DNA Binding Double-stranded DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chondrocyte Differentiation DNA Replication Transcription From RNA Polymerase II Promoter Glial Cell Differentiation Principal Sensory Nucleus Of Trigeminal Nerve Development Anterior Commissure Morphogenesis Hindbrain Development Negative Regulation Of DNA Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter Clara Cell Differentiation Type I Pneumocyte Differentiation Type II Pneumocyte Differentiation Lung Ciliated Cell Differentiation Commissural Neuron Axon Guidance Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Immune Response
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23419831)
Protein-Protein Interactions		3 interactors: NFIC NFIX RFX1	14 interactors: ABL1 ADD1 HIVEP2 HMGB1 MAGED1 NFIB NFIC NFIX RFX2 RFX3 SMAD1 SMAD4 SMAD9 TADA3
Entrez ID		4781	5989
HPRD ID		09008	02476
Ensembl ID		ENSG00000147862	ENSG00000132005
Uniprot IDs		O00712 Q5VW26 Q5VW27 Q5VW28 Q5VW30	P22670
PDB IDs			1DP7
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter DNA Replication Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Cerebellar Granule Cell Differentiation Cerebellar Granular Layer Morphogenesis RNA Metabolic Process Cerebellar Granular Layer Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cerebellar Cortex Formation Cellular Macromolecule Biosynthetic Process Cell Differentiation In Hindbrain Macromolecule Biosynthetic Process Cerebellar Purkinje Cell Layer Development Astrocyte Differentiation Cerebellar Cortex Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Cerebellum Morphogenesis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Hindbrain Morphogenesis Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cerebellar Cortex Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Odontogenesis Of Dentin-containing Tooth Cerebellum Development Metencephalon Development Odontogenesis Hindbrain Development Negative Regulation Of Cellular Metabolic Process	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Hindbrain Development Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Anatomical Structure Morphogenesis Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Development BMP Signaling Pathway Regulation Of Binding System Development SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Multicellular Organismal Development Mesonephros Development Biosynthetic Process Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		abolished aimed alteration caused colony direct dyrk1a explore finding fluorescent hcc hepatocellular hepg2 mir modulated nfat oncogene overexpression p53 propose regulated reporter suggests suppresses syndrome target targeting tumorigenesis wild	243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol
Tagcloud (Difference) ?		abolished aimed alteration caused colony direct dyrk1a explore finding fluorescent hcc hepatocellular hepg2 mir modulated nfat oncogene overexpression p53 propose regulated reporter suggests suppresses syndrome target targeting tumorigenesis wild	243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol
Tagcloud (Intersection) ?