NFE2L2 and COPS7A

Number of citations of the paper that reports this interaction (PMID 12020345)
3

Data Source:
HPRD (in vitro)

		NFE2L2	COPS7A
Gene Name		nuclear factor, erythroid 2-like 2	COP9 signalosome subunit 7A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Plasma Membrane	Nucleoplasm Cytoplasm COP9 Signalosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Cofactor Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Transcription Regulatory Region DNA Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Proteasomal Ubiquitin-independent Protein Catabolic Process Positive Regulation Of Gene Expression Protein Ubiquitination Positive Regulation Of Blood Coagulation Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Embryonic Development Cellular Response To Hydrogen Peroxide Cellular Response To Tumor Necrosis Factor Cellular Response To Fluid Shear Stress Cellular Response To Laminar Fluid Shear Stress Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Cell Death Regulation Of Removal Of Superoxide Radicals Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process	Cullin Deneddylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: ATF4 BPTF CASP1 CASP3 CHD6 COPS7A CREB3 CREBBP DYT10 EIF2AK3 GSK3B JUN JUND KEAP1 KPNA3 MAFF MAFG MAFK MAPK7 NCOR2 NFE2 NFE2L3 PMF1 PPARG PRKCA PRKCD PRKCG PRKCH PRKCQ RBMX SUMO1 TNNT1 TRIM24 UBE2E2 WAC	21 interactors: COPS2 COPS3 COPS4 COPS5 COPS8 CSNK2A1 CSNK2B CUL1 CUL5 EIF3E GPS1 JUN NFE2L2 PMF1 PPBP PRKD1 PSMD4 PTGS2 RAF1 TOM1L1 TP53
Entrez ID		4780	50813
HPRD ID		02732	16736
Ensembl ID		ENSG00000116044	ENSG00000111652
Uniprot IDs		Q16236	Q567U8 Q9UBW8
PDB IDs		2FLU 2LZ1 3ZGC
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Response To Stress Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Cellular Response To Organic Substance Regulation Of Metabolic Process Transcription, DNA-templated Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Response To Organic Substance Regulation Of Body Fluid Levels Regulation Of Apoptotic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cell Death Response To Stimulus Transcription From RNA Polymerase II Promoter Response To Wounding Cellular Metabolic Process Negative Regulation Of Cell Death Positive Regulation Of Protein Metabolic Process Blood Coagulation Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Hemostasis Cellular Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Innate Immune Response Regulation Of Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cellular Response To Stimulus Regulation Of Cellular Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hydrolase Activity	Cullin Deneddylation Protein Deneddylation Protein Modification By Small Protein Removal Regulation Of Cell Proliferation Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Protein Modification Process Regulation Of Cell Cycle Regulation Of Protein Metabolic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Cycle Signal Transduction Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Metabolic Process Positive Regulation Of Protein Modification Process Cellular Metabolic Process Signaling Cellular Response To Stimulus Regulation Of Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Cell Communication Apoptotic Process Programmed Cell Death Regulation Of Catalytic Activity Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of Signaling Mitotic Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Metabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Signal Transduction Cellular Protein Catabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Cell Cycle Apoptotic Signaling Pathway Protein Catabolic Process Regulation Of Cellular Process Intracellular Signal Transduction Negative Regulation Of Cell Death Response To Stimulus Mitotic Cell Cycle Process
Tagcloud ?		adapt anionic cannabidiol cannabinoid cbd combinatorial endowed gbm gsc gscs id1 mes modulators pn proneural psychoactive redox regrowth renewal reprogramming resist ros slc7a11 solute sox2 taqman therapeutics xc xct	abomasum actb b2m blat butterfat calculating coro1b cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Difference) ?		adapt anionic cannabidiol cannabinoid cbd combinatorial endowed gbm gsc gscs id1 mes modulators pn proneural psychoactive redox regrowth renewal reprogramming resist ros slc7a11 solute sox2 taqman therapeutics xc xct	abomasum actb b2m blat butterfat calculating coro1b cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Intersection) ?