NBN and RNF8

  • Number of citations of the paper that reports this interaction (PMID 23115235)
  • 1
  • Data Source:
  • BioGRID (enzymatic study)

NBN

RNF8

Gene Name nibrin ring finger protein 8, E3 ubiquitin protein ligase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 27 interactors: ATF2 ATM ATR BRCA1 CCNE1 CDK9 CHEK2 DCLRE1C EP300 FANCD2 H2AFX MDC1 MRE11A NCL PRKDC RAD18 RAD50 RECQL5 RNF8 SIRT1 TERF1 TLK1 TREX1 UBE2D1 UBE2N XRCC4 XRCC5 35 interactors: BLM CCDC85B CEP44 CHD4 CHEK2 EXOSC2 H2AFX HIST2H2AC HIST2H2BE HOMEZ JMJD1C KDM4A MAD1L1 MDC1 MDM2 NBN PCNA PNMA2 RBFOX2 RXRA SEPT3 TMEM79 UBC UBE2D1 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2V1 UBE2V2 UBE2W VCP WASL YEATS4
Entrez ID 4683 9025
HPRD ID 04050 11521
Ensembl ID ENSG00000104320 ENSG00000112130
Uniprot IDs O60934 O76064
PDB IDs 2CSW 2PIE 4AYC 4EPO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5yrs  atm  atr  brfr  category  cohorts  ddr  decisions  fail  gains  gleason  guided  igrt  mre11a  nibrin  pca  precision  predictor  predicts  prkdc  prostatectomy  psa  rad50  radioresistance  radiotherapy  radp  sensing  sensors  wald 
53bp1  atm  brca1  cdk1  comparatively  coordinates  cytosol  ddr  enables  exit  flanking  genotoxic  h2a  homologous  impairs  interphase  joining  kinetochores  ligases  localize  mitosis  mitotic  plk1  properly  recombination  rnf168  s1618  spatiotemporally  ubiquitinated 
Tagcloud (Difference) ?
5yrs  atr  brfr  category  cohorts  decisions  fail  gains  gleason  guided  igrt  mre11a  nibrin  pca  precision  predictor  predicts  prkdc  prostatectomy  psa  rad50  radioresistance  radiotherapy  radp  sensing  sensors  wald 
53bp1  brca1  cdk1  comparatively  coordinates  cytosol  enables  exit  flanking  genotoxic  h2a  homologous  impairs  interphase  joining  kinetochores  ligases  localize  mitosis  mitotic  plk1  properly  recombination  rnf168  s1618  spatiotemporally  ubiquitinated 
Tagcloud (Intersection) ?
atm  ddr