ASS1 and AKTIP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASS1	AKTIP
Gene Name		argininosuccinate synthase 1	AKT interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrial Outer Membrane Lysosome Endoplasmic Reticulum Cytosol Perikaryon Extracellular Vesicular Exosome Cell Body Fiber	Nucleolus Cytoplasm Golgi Apparatus Plasma Membrane HOPS Complex FHF Complex
	Molecular Function	Argininosuccinate Synthase Activity Protein Binding ATP Binding Toxic Substance Binding Amino Acid Binding Poly(A) RNA Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Urea Cycle Citrulline Metabolic Process Argininosuccinate Metabolic Process Kidney Development Liver Development Arginine Biosynthetic Process Aspartate Metabolic Process Acute-phase Response Midgut Development Aging Response To Nutrient Response To Zinc Ion Response To Mycotoxin Response To Estradiol Cellular Nitrogen Compound Metabolic Process Response To Drug Small Molecule Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Growth Hormone Diaphragm Development Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Cellular Response To Ammonium Ion Cellular Response To CAMP Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Cellular Response To Glucagon Stimulus Cellular Response To Oleic Acid Cellular Response To Amine Stimulus Cellular Response To Laminar Fluid Shear Stress Cellular Response To Dexamethasone Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion	Positive Regulation Of Protein Phosphorylation Apoptotic Process Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Protein Ubiquitination Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport
Pathways		Urea cycle Metabolism of amino acids and derivatives
Drugs		L-Arginine L-Aspartic Acid L-Citrulline Adenosine triphosphate
Diseases
GWAS
Protein-Protein Interactions		12 interactors: AKTIP APP ARAF ASCC2 ELN JAK2 MLH1 MT2A PTPN1 TERF1 TERF2 USP4	23 interactors: AKT1 ASS1 C10orf2 CTBP2 DZIP3 EXOC7 FAM160A2 GTF3C1 HOOK1 HOOK2 HOOK3 IMMT KIAA1377 MARCH5 PDPK1 POLA2 RPA1 TRIM23 TRIM41 UTP14A VPS16 VPS18 VPS41
Entrez ID		445	64400
HPRD ID		04590	07467
Ensembl ID		ENSG00000130707	ENSG00000166971
Uniprot IDs		B4E395 P00966 Q5T6L4	Q9H8T0
PDB IDs		2NZ2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Proteolysis Negative Regulation Of DNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Interferon-gamma-mediated Signaling Pathway Regulation Of Telomere Maintenance Cellular Copper Ion Homeostasis Cellular Response To Interferon-gamma RNA-dependent DNA Replication Regulation Of Interferon-gamma-mediated Signaling Pathway Copper Ion Homeostasis JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Response To Interferon-gamma Growth Hormone Receptor Signaling Pathway Response To Interferon-gamma Cellular Response To Growth Hormone Stimulus Regulation Of Protein Phosphorylation Telomere Maintenance Via Telomere Lengthening Regulation Of Proteasomal Protein Catabolic Process Cellular Component Assembly Response To Growth Hormone Regulation Of Binding Immune Response Negative Regulation Of Cellular Metabolic Process Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of DNA Replication Regulation Of Cellular Process Regulation Of Phosphorylation Organelle Organization Regulation Of Metabolic Process JAK-STAT Cascade Homeostatic Process Regulation Of Phosphorus Metabolic Process Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Histone H3-Y41 Phosphorylation Meiotic Metaphase I Plate Congression Host Programmed Cell Death Induced By Symbiont Meiotic Spindle Midzone Assembly Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Cellular Localization Cell Aging	Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Protein Localization Organelle Organization Endosomal Transport Endomembrane System Organization Cytoplasmic Transport Cellular Localization Intracellular Transport Establishment Of Localization In Cell Regulation Of Vesicle Fusion Protein Localization To Organelle DNA-dependent DNA Replication Telomere Maintenance Via Semi-conservative Replication Protein Ubiquitination Cellular Protein Localization Nuclear DNA Replication Telomere Maintenance Via Recombination Protein Modification By Small Protein Conjugation Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Response To Epidermal Growth Factor Stimulus Vesicle-mediated Transport Positive Regulation Of Protein Localization To Plasma Membrane Response To Epidermal Growth Factor Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Protein Import Into Nucleus, Translocation Regulation Of Vesicle-mediated Transport DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening G1/S Transition Of Mitotic Cell Cycle Response To Fluid Shear Stress Cytoplasmic Microtubule Organization Viral Entry Into Host Cell Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Temperature Stimulus Viral Life Cycle Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Entry Into Host Cell Argininosuccinate Metabolic Process Regulation Of Vacuole Fusion, Non-autophagic
Tagcloud ?			apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works
Tagcloud (Difference) ?			apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works
Tagcloud (Intersection) ?