MPP3 and SF3B3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		MPP3	SF3B3
Gene Name		membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	splicing factor 3b, subunit 3, 130kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Guanylate Kinase Activity PDZ Domain Binding	RNA Binding Protein Binding
	Biological Process	Signal Transduction Nucleotide Phosphorylation	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing Protein Complex Assembly RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: APP ARL2BP CADM1 CCDC137 CRABP1 ERBB2IP EZR FAM171B GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A MCM2 MDH1 NOA1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TIRAP TMEM37 TRAF2 TRIM41 ZPR1	27 interactors: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579
Entrez ID		4356	23450
HPRD ID		03069	12027
Ensembl ID		ENSG00000161647
Uniprot IDs		Q13368	A8K6V3 Q15393
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Cell Growth Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Protein Binding Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Binding Regulation Of Protein Homodimerization Activity Growth Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Cycle MRNA Metabolic Process Positive Regulation Of Binding Cellular Response To Epidermal Growth Factor Stimulus Multicellular Organismal Development Asymmetric Protein Localization System Development Establishment Or Maintenance Of Apical/basal Cell Polarity RNA Processing DNA Strand Elongation Involved In DNA Replication Positive Regulation Of Signal Transduction Response To Epidermal Growth Factor DNA Strand Elongation Organelle Organization Exocytosis RNA Splicing Signaling Cellular Protein Localization G1/S Transition Of Mitotic Cell Cycle Cell Communication Nervous System Development Receptor Internalization Cellular Component Assembly Positive Regulation Of Interleukin-15 Production Nuclear Speck Organization Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Positive Regulation Of Neurotrophin Production Dermatan Sulfate Catabolic Process Positive Regulation Of Nonmotile Primary Cilium Assembly TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Pre-mRNA Catabolic Process DNA Endoreduplication Signal Transduction Positive Regulation Of Innate Immune Response Protein Localization Regulation Of Phosphorus Metabolic Process	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Shape Regulation Of Cell Death Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Process Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Respiratory Burst After Phagocytosis Negative Regulation Of Thymidylate Synthase Biosynthetic Process Negative Regulation Of Potassium Ion Export Cardiac Muscle Contraction Regulation Of Transcription From RNA Polymerase II Promoter Metabolic Process Heart Contraction Positive Regulation Of Response To DNA Damage Stimulus Peptidyl-amino Acid Modification Threonylcarbamoyladenosine Biosynthetic Process Leukocyte Migration Involved In Immune Response Regulation Of Heart Rate By Hormone N-acetylmannosamine Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Ossification Response To Growth Factor Positive Regulation Of Cell Death Actin Polymerization-dependent Cell Motility Striated Muscle Contraction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Peptide Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway N-acetylneuraminate Catabolic Process
Tagcloud ?		17q12 abundant backcross brca1 carboxy cdnas clustering conservation cytoskeleton dlgh3 guanylate homologue homologues interspecific kb maguks mapped murine originally pdz presumably proximity sh3 skeletal subclass testis transcript translated virtue	advance albeit ascertain atlas cohorts document doi dx endocrine fulvestrant lcc2 lcc9 mcf modern modpathol november oncotype online paraffin parts publication publicly qrt sets sf3b1 splicing tamoxifen
Tagcloud (Difference) ?		17q12 abundant backcross brca1 carboxy cdnas clustering conservation cytoskeleton dlgh3 guanylate homologue homologues interspecific kb maguks mapped murine originally pdz presumably proximity sh3 skeletal subclass testis transcript translated virtue	advance albeit ascertain atlas cohorts document doi dx endocrine fulvestrant lcc2 lcc9 mcf modern modpathol november oncotype online paraffin parts publication publicly qrt sets sf3b1 splicing tamoxifen
Tagcloud (Intersection) ?