MPP3 and INSM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		MPP3	INSM1
Description		MAGUK p55 scaffold protein 3	INSM transcriptional repressor 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Adherens Junction Membrane Apical Plasma Membrane Anchoring Junction	Nucleus Nucleoplasm Transcription Repressor Complex
	Molecular Function	Protein Binding PDZ Domain Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Zinc Ion Binding Cyclin Binding Chromatin DNA Binding Histone Deacetylase Binding Metal Ion Binding Molecular Adaptor Activity
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Phosphorylation Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Type B Pancreatic Cell Development Noradrenergic Neuron Development Nervous System Development Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Regulation Of Gene Expression Regulation Of Cell Cycle Process Cell Migration Cell Differentiation Neuron Differentiation Positive Regulation Of Cell Migration Endocrine Pancreas Development Endocrine System Development Regulation Of Cell Population Proliferation Norepinephrine Biosynthetic Process Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cell Differentiation Regulation Of Cell Cycle Transdifferentiation Adrenal Chromaffin Cell Differentiation Sympathetic Ganglion Development Positive Regulation Of Neural Precursor Cell Proliferation
Pathways			Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
Drugs
Diseases
GWAS		HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068)
Interacting Genes		37 interacting genes: APP ARL2BP BTBD1 CADM1 CCDC137 CRABP1 ERBIN EZR FAM171B FBXO7 GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A MCM2 MDH1 NOA1 PKNOX1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TIRAP TMEM37 TRAF2 TRIM41 ZNF655 ZPR1	5 interacting genes: CCND1 KDM1A MPP3 SORBS1 TUBB3
Entrez ID		4356	3642
HPRD ID		03069	02480
Ensembl ID		ENSG00000161647	ENSG00000173404
Uniprot IDs		D3DX46 Q13368	Q01101
PDB IDs			2LV2 3ZMS 8JPY 8JQ1 8K81
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Transcription Corepressor Activity Response To UV Re-entry Into Mitotic Cell Cycle Response To Ionizing Radiation Cyclin D1-CDK4 Complex Cyclin D1-CDK6 Complex Adherens Junction Netrin Receptor Binding Dorsal Root Ganglion Development Response To Fungicide MRF Binding Guanine Metabolic Process Protein Demethylase Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?