MPP3 and CADM1

Number of citations of the paper that reports this interaction (PMID 13679854)
21

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MPP3	CADM1
Gene Name		membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	cell adhesion molecule 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane	Plasma Membrane Cell-cell Junction Synaptic Vesicle Integral Component Of Membrane Basolateral Plasma Membrane Axon Dendrite Extracellular Vesicular Exosome
	Molecular Function	Guanylate Kinase Activity PDZ Domain Binding	Receptor Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Signal Transduction Nucleotide Phosphorylation	Liver Development T Cell Mediated Cytotoxicity Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Spermatogenesis Synapse Assembly Brain Development Cell Recognition Unidimensional Cell Growth Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell Differentiation Cell Junction Assembly Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Cell-cell Junction Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Cytokine Secretion Activated T Cell Proliferation Detection Of Stimulus Bone Development
Pathways			Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS			Cardiovascular disease risk factors ( 20838585) Obesity-related traits ( 23251661)
Protein-Protein Interactions		33 interactors: APP ARL2BP CADM1 CCDC137 CRABP1 ERBB2IP EZR FAM171B GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A MCM2 MDH1 NOA1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TIRAP TMEM37 TRAF2 TRIM41 ZPR1	6 interactors: ATF7IP CASK EPB41L3 MPP3 PSMA6 SDCBP
Entrez ID		4356	23705
HPRD ID		03069	05746
Ensembl ID		ENSG00000161647	ENSG00000182985
Uniprot IDs		Q13368	A0A4Z1 Q9BY67
PDB IDs			3BIN 4H5S
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Cell Growth Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Protein Binding Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Binding Regulation Of Protein Homodimerization Activity Growth Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Cycle MRNA Metabolic Process Positive Regulation Of Binding Cellular Response To Epidermal Growth Factor Stimulus Multicellular Organismal Development Asymmetric Protein Localization System Development Establishment Or Maintenance Of Apical/basal Cell Polarity RNA Processing DNA Strand Elongation Involved In DNA Replication Positive Regulation Of Signal Transduction Response To Epidermal Growth Factor DNA Strand Elongation Organelle Organization Exocytosis RNA Splicing Signaling Cellular Protein Localization G1/S Transition Of Mitotic Cell Cycle Cell Communication Nervous System Development Receptor Internalization Cellular Component Assembly Positive Regulation Of Interleukin-15 Production Nuclear Speck Organization Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Positive Regulation Of Neurotrophin Production Dermatan Sulfate Catabolic Process Positive Regulation Of Nonmotile Primary Cilium Assembly TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Pre-mRNA Catabolic Process DNA Endoreduplication Signal Transduction Positive Regulation Of Innate Immune Response Protein Localization Regulation Of Phosphorus Metabolic Process	Nucleotide Phosphorylation
Tagcloud ?		17q12 abundant backcross brca1 carboxy cdnas clustering conservation cytoskeleton dlgh3 guanylate homologue homologues interspecific kb maguks mapped murine originally pdz presumably proximity sh3 skeletal subclass testis transcript translated virtue	125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim bmpr1b cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a
Tagcloud (Difference) ?		17q12 abundant backcross brca1 carboxy cdnas clustering conservation cytoskeleton dlgh3 guanylate homologue homologues interspecific kb maguks mapped murine originally pdz presumably proximity sh3 skeletal subclass testis transcript translated virtue	125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim bmpr1b cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a
Tagcloud (Intersection) ?