MPP3 and GNG7

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MPP3	GNG7
Gene Name		membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	guanine nucleotide binding protein (G protein), gamma 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane	Heterotrimeric G-protein Complex Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Guanylate Kinase Activity PDZ Domain Binding	Signal Transducer Activity
	Biological Process	Signal Transduction Nucleotide Phosphorylation	Behavioral Fear Response Energy Reserve Metabolic Process Receptor Guanylyl Cyclase Signaling Pathway G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Locomotory Behavior Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Small Molecule Metabolic Process Regulation Of Adenylate Cyclase Activity Cellular Response To Glucagon Stimulus
Pathways			Signaling by GPCR Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 1 Integration of energy metabolism G alpha (s) signalling events Activation of GABAB receptors Glucagon-type ligand receptors G beta:gamma signalling through PLC beta Signaling by Wnt Metabolic disorders of biological oxidation enzymes G protein gated Potassium channels Gastrin-CREB signalling pathway via PKC and MAPK Thromboxane signalling through TP receptor G alpha (z) signalling events G alpha (i) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell ADP signalling through P2Y purinoceptor 12 Glucagon signaling in metabolic regulation Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Inwardly rectifying K+ channels G-protein beta:gamma signalling Opioid Signalling Activation of Kainate Receptors upon glutamate binding Aquaporin-mediated transport Adrenaline,noradrenaline inhibits insulin secretion G alpha (q) signalling events GPCR downstream signaling Platelet homeostasis Platelet activation, signaling and aggregation Transmission across Chemical Synapses G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signal amplification Potassium Channels G beta:gamma signalling through PI3Kgamma G alpha (12/13) signalling events Class B/2 (Secretin family receptors) Prostacyclin signalling through prostacyclin receptor GABA B receptor activation GABA receptor activation Activation of G protein gated Potassium channels Vasopressin regulates renal water homeostasis via Aquaporins Regulation of insulin secretion GPCR ligand binding beta-catenin independent WNT signaling Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Ca2+ pathway G-protein activation
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: APP ARL2BP CADM1 CCDC137 CRABP1 ERBB2IP EZR FAM171B GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A MCM2 MDH1 NOA1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TIRAP TMEM37 TRAF2 TRIM41 ZPR1	7 interactors: ACP6 GNB1 GNB2 GNB3 GNB4 GNB5 MPP3
Entrez ID		4356	2788
HPRD ID		03069	10376
Ensembl ID		ENSG00000161647	ENSG00000176533
Uniprot IDs		Q13368	O60262
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Cell Growth Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Protein Binding Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Binding Regulation Of Protein Homodimerization Activity Growth Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Cycle MRNA Metabolic Process Positive Regulation Of Binding Cellular Response To Epidermal Growth Factor Stimulus Multicellular Organismal Development Asymmetric Protein Localization System Development Establishment Or Maintenance Of Apical/basal Cell Polarity RNA Processing DNA Strand Elongation Involved In DNA Replication Positive Regulation Of Signal Transduction Response To Epidermal Growth Factor DNA Strand Elongation Organelle Organization Exocytosis RNA Splicing Signaling Cellular Protein Localization G1/S Transition Of Mitotic Cell Cycle Cell Communication Nervous System Development Receptor Internalization Cellular Component Assembly Positive Regulation Of Interleukin-15 Production Nuclear Speck Organization Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Positive Regulation Of Neurotrophin Production Dermatan Sulfate Catabolic Process Positive Regulation Of Nonmotile Primary Cilium Assembly TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Pre-mRNA Catabolic Process DNA Endoreduplication Signal Transduction Positive Regulation Of Innate Immune Response Protein Localization Regulation Of Phosphorus Metabolic Process	Cellular Response To Glucagon Stimulus Response To Glucagon Energy Reserve Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Generation Of Precursor Metabolites And Energy Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Cellular Response To Hormone Stimulus Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Response To Organonitrogen Compound Response To Hormone Small Molecule Metabolic Process G-protein Coupled Receptor Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Lysobisphosphatidic Acid Metabolic Process Cellular Response To Light Stimulus Phototransduction Detection Of Light Stimulus Oxidation-reduction Process Synaptic Transmission Signal Transduction Cellular Response To Radiation Signaling Cellular Response To Organic Substance Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Cell Communication Negative Regulation Of Voltage-gated Calcium Channel Activity Cell-cell Signaling Cardiac Muscle Cell Apoptotic Process Muscle Cell Apoptotic Process Cellular Response To Stimulus Response To Organic Substance Cellular Response To Prostaglandin E Stimulus Response To Light Stimulus G-protein Coupled Acetylcholine Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Response To Prostaglandin E Cellular Response To Prostaglandin Stimulus Negative Regulation Of Cation Channel Activity Regulation Of Voltage-gated Calcium Channel Activity Response To Radiation Cell Surface Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus
Tagcloud ?		17q12 abundant backcross brca1 carboxy cdnas clustering conservation cytoskeleton dlgh3 guanylate homologue homologues interspecific kb maguks mapped murine originally pdz presumably proximity sh3 skeletal subclass testis transcript translated virtue	adjust adora2a avp cart cecal clp intramuscular ku myh7 oxt pde1b pdyn preconditioning prkcd prkch puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin
Tagcloud (Difference) ?		17q12 abundant backcross brca1 carboxy cdnas clustering conservation cytoskeleton dlgh3 guanylate homologue homologues interspecific kb maguks mapped murine originally pdz presumably proximity sh3 skeletal subclass testis transcript translated virtue	adjust adora2a avp cart cecal clp intramuscular ku myh7 oxt pde1b pdyn preconditioning prkcd prkch puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin
Tagcloud (Intersection) ?