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BMF
Gene Name
Bcl2 modifying factor
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Acrosomal Vesicle
Mitochondrial Outer Membrane
Cytosol
Plasma Membrane
Myosin Complex
Molecular Function
Protein Binding
Biological Process
Apoptotic Process
Positive Regulation Of Protein Homooligomerization
Anoikis
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Negative Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Programmed Cell Death
Activation of BH3-only proteins
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Activation of BMF and translocation to mitochondria
Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Dehydroepiandrosterone sulphate levels (
21533175
)
Ewing sarcoma (
22327514
)
Protein-protein Interactions
15 interactors:
BCL2
BCL2A1
BCL2L1
BCL2L2
CXCL9
DYNLL1
DYNLL2
MAPK8
MCL1
MYO5A
NNMT
REL
SEC14L4
TCF12
TFIP11
Entrez ID
90427
HPRD ID
05881
Ensembl ID
ENSG00000104081
Uniprot IDs
Q96LC9
PDB IDs
Enriched GO Terms of Interacting Partners
?
Intrinsic Apoptotic Signaling Pathway
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrion Organization
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Intrinsic Apoptotic Signaling Pathway
Apoptotic Process
Positive Regulation Of Mitochondrion Organization
Regulation Of Signal Transduction
Programmed Cell Death
Cell Death
Death
Regulation Of Cell Death
Negative Regulation Of Anoikis
Regulation Of Signaling
Regulation Of Anoikis
Positive Regulation Of Intracellular Transport
Positive Regulation Of Signal Transduction
Intracellular Signal Transduction
Negative Regulation Of Apoptotic Signaling Pathway
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Cell Death
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Transport
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Apoptotic Mitochondrial Changes
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Immune System Process
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of Cellular Localization
Regulation Of Neuron Death
Cellular Response To Stimulus
Regulation Of Establishment Of Protein Localization
Response To Stimulus
Response To Organic Substance
Response To Cytokine
Melanin Metabolic Process
Positive Regulation Of Transport
Tagcloud
?
70z
bcgf
begin
bpa
call
chromatographic
die
discrete
etc
glycoproteins
glycosylated
hcgf
helper
heterogeneously
ig
implying
lymphokine
lymphokines
mcgf
mildly
permeation
psf
purifies
purify
splenic
supernatants
synthesize
variously
wehi