BMF and CTAG1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BMF	CTAG1A
Description		Bcl2 modifying factor	cancer/testis antigen 1A
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GO Annotations	Cellular Component	Mitochondrial Outer Membrane Cytosol Plasma Membrane Myosin Complex	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Apoptotic Process Negative Regulation Of Autophagy Positive Regulation Of Protein-containing Complex Assembly Cellular Response To UV Positive Regulation Of Apoptotic Process Anoikis Positive Regulation Of Release Of Cytochrome C From Mitochondria	TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of BMF and translocation to mitochondria
Drugs
Diseases
GWAS		B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Chronic lymphocytic leukemia ( 24292274 26956414 28165464) Dehydroepiandrosterone sulphate levels ( 21533175) Endometrial cancer ( 27135401 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Endometrial endometrioid carcinoma ( 27135401) Ewing sarcoma ( 22327514) Hip circumference adjusted for BMI ( 34021172) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lymphocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Triglyceride levels ( 32203549)
Interacting Genes		26 interacting genes: AQP1 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BCL2L2-PABPN1 CTAG1A CTAG1B CXCL9 DYNLL1 DYNLL2 GPSM3 LCN2 MAPK8 MCL1 MGAT5B MYO5A NNMT RECK REL SEC14L4 SHC3 TCF12 TFIP11 TRIM54	76 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1B CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX
Entrez ID		90427	246100
HPRD ID		05881	06607
Ensembl ID		ENSG00000104081	ENSG00000268651
Uniprot IDs		Q96LC9	P78358
PDB IDs		7CNU 8IQK 8IQL 8IQM 8R58	1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1
Enriched GO Terms of Interacting Partners?		Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Channel Activity Release Of Cytochrome C From Mitochondria Extrinsic Apoptotic Signaling Pathway Apoptotic Mitochondrial Changes Bcl-2 Family Protein Complex Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage BH3 Domain Binding Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Mitochondrial Outer Membrane Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death DNA Damage Response Mitochondrion Organization Negative Regulation Of Apoptotic Process Negative Regulation Of Anoikis Negative Regulation Of Programmed Cell Death Dendritic Cell Apoptotic Process Cellular Response To Stress Regulation Of Anoikis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Microtubule Associated Complex Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Stress Programmed Cell Death Cell Death Cell Surface Receptor Signaling Pathway Negative Regulation Of Dendritic Cell Apoptotic Process Response To Reactive Oxygen Species Regulation Of Apoptotic Process Intracellular Signal Transduction Regulation Of Programmed Cell Death Mitochondrial Fusion TRNA Threonylcarbamoyladenosine Metabolic Process Response To Radiation Response To Hydrogen Peroxide Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To External Biotic Stimulus Programmed Cell Death Involved In Cell Development Regulation Of Neuron Apoptotic Process Negative Regulation Of Autophagy Cytoplasmic Dynein Complex Cellular Response To Reactive Oxygen Species Nuclear Membrane Identical Protein Binding Cytoplasm Metanephric Descending Thin Limb Development Cellular Response To Decreased Oxygen Levels	Protein Binding Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteasomal Protein Catabolic Process Skeletal Muscle Atrophy Regulation Of Proteasomal Protein Catabolic Process Protein Targeting To ER Regulation Of Protein Ubiquitination Cytoplasm Skeletal Muscle Adaptation Striated Muscle Atrophy Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
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