MEP1A and SCT

Number of citations of the paper that reports this interaction (PubMedID 11278902)
0

Data Source:
HPRD (in vitro)

		MEP1A	SCT
Description		meprin A subunit alpha	secretin
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane Meprin A Complex Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Metallodipeptidase Activity	G Protein-coupled Receptor Binding Signaling Receptor Binding Hormone Activity Protein Binding Digestive Hormone Activity
	Biological Process	Proteolysis Epidermal Growth Factor Receptor Ligand Maturation Signaling Receptor Ligand Precursor Processing	Diet Induced Thermogenesis Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Brain Development Intracellular Water Homeostasis Hippocampus Development Pancreatic Juice Secretion Response To Nutrient Levels Regulation Of Appetite Regulation Of Synaptic Plasticity Embryonic Digestive Tract Development Positive Regulation Of Lipid Catabolic Process Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of Somatostatin Secretion Positive Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Gastrin-induced Gastric Acid Secretion
Pathways			G alpha (s) signalling events Glucagon-type ligand receptors
Drugs
Diseases
GWAS
Interacting Genes		18 interacting genes: AGT CCK FN1 GCG GNRH1 GRP KNG1 LAMA1 LAMA5 MEP1B NPY NTS PLG POMC PTH SCT TAC1 VIP	8 interacting genes: HGS HOXA1 MEIS2 MEP1A MEP1B SCTR USHBP1 VIPR1
Entrez ID		4224	6343
HPRD ID		02666	08354
Ensembl ID		ENSG00000112818	ENSG00000070031
Uniprot IDs		B7ZL91 Q16819	P09683
PDB IDs		7UAB 7UAC 7UAE 7UAF 7UAI	6WI9 6WZG 7D3S
Enriched GO Terms of Interacting Partners?		Hormone Activity Extracellular Space Extracellular Region Receptor Ligand Activity Signaling Receptor Binding G Protein-coupled Receptor Signaling Pathway Neuropeptide Hormone Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Positive Regulation Of Cell Communication Positive Regulation Of Signaling Signal Transduction Neuropeptide Signaling Pathway Positive Regulation Of Signal Transduction Peptide Hormone Receptor Binding Antifungal Humoral Response Humoral Immune Response Regulation Of Hormone Secretion Regulation Of Signaling Regulation Of Multicellular Organismal Process Response To Yeast Regulation Of Hormone Levels Negative Regulation Of Multicellular Organismal Process Regulation Of Secretion By Cell Regulation Of Biological Quality Cell-cell Signaling Regulation Of Secretion Signaling Regulation Of Appetite Cell Communication Regulation Of Cell Communication Extracellular Matrix Blood Microparticle Killing Of Cells Of Another Organism Regulation Of Cell Adhesion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Hormone Secretion Regulation Of Cell Population Proliferation Regulation Of Corticosterone Secretion Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Defense Response To Fungus Response To External Biotic Stimulus Regulation Of Blood Pressure Response To Hormone Defense Response Regulation Of Cell Migration Response To Fungus Antibacterial Humoral Response Cell Killing Platelet Alpha Granule Lumen	Meprin A Complex G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding Visual Behavior Semicircular Canal Formation Secretin Receptor Activity Abducens Nerve Formation Optokinetic Behavior Positive Regulation Of Cardiac Muscle Myoblast Proliferation Epidermal Growth Factor Receptor Ligand Maturation Metalloendopeptidase Activity Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity ESCRT-0 Complex Metallopeptidase Activity Phagocytic Vesicle Lumen Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
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