SCT and VIPR1

Number of citations of the paper that reports this interaction (PubMedID 12133828)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		SCT	VIPR1
Description		secretin	vasoactive intestinal peptide receptor 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Membrane Receptor Complex
	Molecular Function	G Protein-coupled Receptor Binding Signaling Receptor Binding Hormone Activity Protein Binding Digestive Hormone Activity	Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Vasoactive Intestinal Polypeptide Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding
	Biological Process	Diet Induced Thermogenesis Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Brain Development Intracellular Water Homeostasis Hippocampus Development Pancreatic Juice Secretion Response To Nutrient Levels Regulation Of Appetite Regulation Of Synaptic Plasticity Embryonic Digestive Tract Development Positive Regulation Of Lipid Catabolic Process Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of Somatostatin Secretion Positive Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Gastrin-induced Gastric Acid Secretion	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors	G alpha (s) signalling events Glucagon-type ligand receptors
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Cerebrospinal fluid clusterin levels ( 26545630) Hip circumference adjusted for BMI ( 28552196) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		8 interacting genes: HGS HOXA1 MEIS2 MEP1A MEP1B SCTR USHBP1 VIPR1	16 interacting genes: ADCYAP1 CALM1 GNAI1 GNAQ GNAS GPRASP1 PFN1 PRDM5 PTMA RAMP1 RAMP2 RAMP3 SCT TINF2 VIP WASL
Entrez ID		6343	7433
HPRD ID		08354	01890
Ensembl ID		ENSG00000070031	ENSG00000114812
Uniprot IDs		P09683	B4DNY6 P32241
PDB IDs		6WI9 6WZG 7D3S	1OF2 1OGT 3B3I 3B6S 3DTX 3HCV 5DEF 5DEG 5IB1 5IB2 5IB3 5IB4 5IB5 6VN7 7ALO 8E3Y 8E3Z
Enriched GO Terms of Interacting Partners?		Meprin A Complex G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding Visual Behavior Semicircular Canal Formation Secretin Receptor Activity Abducens Nerve Formation Optokinetic Behavior Positive Regulation Of Cardiac Muscle Myoblast Proliferation Epidermal Growth Factor Receptor Ligand Maturation Metalloendopeptidase Activity Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity ESCRT-0 Complex Metallopeptidase Activity Phagocytic Vesicle Lumen Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP/PKA Signal Transduction Amylin Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Calcitonin Family Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Guanyl Nucleotide Binding Type 2 Vasoactive Intestinal Polypeptide Receptor Binding Type 1 Vasoactive Intestinal Polypeptide Receptor Binding G-protein Beta/gamma-subunit Complex Binding Response To Prostaglandin E Adrenomedullin Receptor Activity Adrenomedullin Receptor Complex Amylin Receptor Activity Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Heterotrimeric G-protein Complex Adenylate Cyclase Regulator Activity Adenylate Cyclase Activator Activity Adrenomedullin Receptor Signaling Pathway Response To Hormone Coreceptor Activity Regulation Of Peptide Hormone Secretion G Protein Activity Receptor Internalization G Protein-coupled Receptor Binding Peptide Hormone Receptor Binding Activation Of Adenylate Cyclase Activity Regulation Of Signal Transduction Regulation Of Hormone Secretion Regulation Of Hormone Levels Neuropeptide Signaling Pathway Regulation Of Protein Localization Regulation Of Body Fluid Levels Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Acidic PH Hormone Activity Positive Regulation Of Lyase Activity Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Biological Quality Positive Regulation Of Cyclase Activity Regulation Of Metabolic Process G Protein-coupled Serotonin Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Cellular Response To Hormone Stimulus
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