SCT and MEP1B

Number of citations of the paper that reports this interaction (PubMedID 11278902)
0

Data Source:
HPRD (in vitro)

		SCT	MEP1B
Description		secretin	meprin A subunit beta
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space Plasma Membrane Membrane Meprin A Complex
	Molecular Function	G Protein-coupled Receptor Binding Signaling Receptor Binding Hormone Activity Protein Binding Digestive Hormone Activity	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Diet Induced Thermogenesis Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Brain Development Intracellular Water Homeostasis Hippocampus Development Pancreatic Juice Secretion Response To Nutrient Levels Regulation Of Appetite Regulation Of Synaptic Plasticity Embryonic Digestive Tract Development Positive Regulation Of Lipid Catabolic Process Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of Somatostatin Secretion Positive Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Gastrin-induced Gastric Acid Secretion	Proteolysis Inflammatory Response
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors
Drugs
Diseases
GWAS			Metabolite levels ( 23823483) TRAIL levels ( 27989323)
Interacting Genes		8 interacting genes: HGS HOXA1 MEIS2 MEP1A MEP1B SCTR USHBP1 VIPR1	13 interacting genes: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT TSPAN8
Entrez ID		6343	4225
HPRD ID		08354	02667
Ensembl ID		ENSG00000070031	ENSG00000141434
Uniprot IDs		P09683	J3QKX5 Q16820
PDB IDs		6WI9 6WZG 7D3S	4GWM 4GWN 7AQ1 7AUW
Enriched GO Terms of Interacting Partners?		Meprin A Complex G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding Visual Behavior Semicircular Canal Formation Secretin Receptor Activity Abducens Nerve Formation Optokinetic Behavior Positive Regulation Of Cardiac Muscle Myoblast Proliferation Epidermal Growth Factor Receptor Ligand Maturation Metalloendopeptidase Activity Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity ESCRT-0 Complex Metallopeptidase Activity Phagocytic Vesicle Lumen Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Hormone Activity Neuropeptide Hormone Activity G Protein-coupled Receptor Signaling Pathway Extracellular Space Feeding Behavior Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Neuropeptide Y Receptor Binding Extracellular Region Positive Regulation Of Hormone Secretion Signaling Receptor Binding Signal Transduction Regulation Of Peptide Hormone Secretion Regulation Of Biological Quality G Protein-coupled Receptor Binding Regulation Of Hormone Levels Cellular Response To Glucagon Stimulus Intestinal Epithelial Cell Differentiation Regulation Of Hormone Secretion Regulation Of Secretion By Cell Regulation Of Body Fluid Levels Regulation Of Transport Positive Regulation Of Secretion By Cell Neuropeptide Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Secretion Positive Regulation Of Secretion Response To Glucagon Receptor Ligand Activity Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Gluconeogenesis Regulation Of Appetite Positive Regulation Of Lipid Metabolic Process Regulation Of Intracellular Protein Transport Positive Regulation Of Lipid Catabolic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Behavior Positive Regulation Of Transport Regulation Of Protein Transport Cellular Response To Peptide Hormone Stimulus Peptidyl-serine Phosphorylation Regulation Of Cellular Localization Regulation Of Establishment Of Protein Localization Positive Regulation Of Glucose Metabolic Process Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Gluconeogenesis Short-day Photoperiodism Negative Regulation Of Coagulation
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